About   Help   FAQ
Impg2 Gene Detail
Summary
  • Symbol
    Impg2
  • Name
    interphotoreceptor matrix proteoglycan 2
  • Synonyms
    IPM200, PG10.2, Spacrcan
  • Feature Type
    protein coding gene
  • IDs
    MGI:3044955
    NCBI Gene: 224224
Location & Maps
more
  • Sequence Map
    Chr16:56204313-56273756 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      69444 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 33.91 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    IMPG2, interphotoreceptor matrix proteoglycan 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    IMPG2, interphotoreceptor matrix proteoglycan 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IPM200, RP56, SPACRCAN, VMD5
  • Links
    NCBI Gene ID: 50939
    neXtProt AC: NX_Q9BZV3

  • Chr Location
    3q12.2-q12.3; chr3:101222546-101320575 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human IMPG2 associations

Human Disease Mouse Models
       Macular Dystrophy, Vitelliform, 5; VMD5   OMIM: 616152
Retinitis Pigmentosa 56; RP56   OMIM: 613581
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032947 VEGA Gene Model | MGI Sequence Detail 69444 C57BL/6J ±  kb
transcript OTTMUST00000082141 VEGA | MGI Sequence Detail 6890 Not Applicable  
polypeptide OTTMUSP00000044018 VEGA | MGI Sequence Detail 1243 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    731 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:90863 Chen Q, et al., SPACRCAN in the interphotoreceptor matrix of the mouse retina: molecular, developmental and promoter analysis. Exp Eye Res. 2003 Jan;76(1):1-14
  • Latest
    J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/13/2016
MGI 6.05
The Jackson Laboratory