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Impg2
Gene Detail
Symbol

Name
ID
Impg2
interphotoreceptor matrix proteoglycan 2
MGI:3044955
Synonyms
IPM200, PG10.2, Spacrcan
Feature Type
protein coding gene
Genetic Map
Chromosome 16
33.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:56204313-56273756 bp, + strand
From VEGA annotation of GRCm38

  69444 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9439  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: IMPG2
Gene Tree: Impg2

Human
homologs
IMPG2, interphotoreceptor matrix proteoglycan 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 50939
neXtProt AC: NX_Q9BZV3

Human Synonyms: IPM200, RP56, SPACRCAN, VMD5

Human Chr (Location): 3q12.2-q12.3; chr3:101222546-101320575 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human IMPG2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Impg2 interacts with 362 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biological_process
Component integral component of membrane, membrane, ...
Function heparin binding, hyaluronic acid binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (8)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 8
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000032947 (Evidence)
Ensembl Gene Model ENSMUSG00000035270 (Evidence)
Entrez Gene 224224 (Evidence)
UniGene 151998
DFCI TC1600971, TC1593992, TC1587330
DoTS DT.94177475, DT.91573830, DT.91326609
NIA Mouse Gene Index U017218
Consensus CDS Project CCDS37358.1
International Mouse Phenotyping Consortium Status Impg2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032947 VEGA Gene Model | MGI Sequence Detail 69444 C57BL/6J ±  kb
transcript OTTMUST00000082141 VEGA | MGI Sequence Detail 6890 Not Applicable 
polypeptide OTTMUSP00000044018 VEGA | MGI Sequence Detail 1243 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(738 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR000082 SEA domain
Protein Ontology PR:000009024 interphotoreceptor matrix proteoglycan 2
References
(Earliest) J:90863 Chen Q, et al., SPACRCAN in the interphotoreceptor matrix of the mouse retina: molecular, developmental and promoter analysis. Exp Eye Res. 2003 Jan;76(1):1-14
(Latest) J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory