Tg(MMTV-Myc)147-9bLed
Transgene Detail
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Symbol: |
Tg(MMTV-Myc)147-9bLed |
Name: |
transgene insertion 147-9b, Philip Leder |
MGI ID: |
MGI:2447512 |
Synonyms: |
147-9b, K strain, MMTV-c-myc, MMTV-cMyc, MMTV-myc, MTV-Sma 147-9b, TG.K |
Transgene: |
Tg(MMTV-Myc)147-9bLed Location: unknown
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Alliance: |
Tg(MMTV-Myc)147-9bLed page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(MMTV-Myc)147-9bLed expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Myc (MGI:97250) |
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Mutation details: The transgene contains the mouse mammary tumor virus promoter and the mouse myelocytomatosis oncogene and the endogenous Myc promoters. The MMTV promoter droved transgenic expression in the spleen, testis, lung, brain, salivary gland, and mammary (J:72130) and preputial gland. Expression of the transgene was not detected in thymus, pancreas, kidney, liver, heart, or muscle. Five to ten copies of the transgene were inserted at the site of integration. The founder mouse that gave rise to this strain carried two insertions of the transgene, which were separated by breeding into lines carrying either Tg(MMTV-cmyc)147-9aLed or Tg(MMTV-cmyc)147-9bLed.
(J:29013)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Transgenic line 147-9b is also called "TG.K." Lines 147-9a and 147-6 also carry this construct. The construct was designated "MMTV/c-myc" or "MTV-Sma" or "MTV-Sma myc" or "MMTV-Sma myc" or "TG.K."
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Original: |
J:29013 Stewart TA, et al., Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell. 1984 Oct;38(3):627-37 |
All: |
9 reference(s) |
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