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Lrit3
Gene Detail
Symbol

Name
ID
Lrit3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
MGI:2685267
Synonyms
LOC242235
Feature Type
protein coding gene
Genetic Map
Chromosome 3
58.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:129787881-129804030 bp, - strand
From VEGA annotation of GRCm38

  16150 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19426  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LRIT3
Gene Tree: Lrit3

Human
homologs
LRIT3, leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 345193
neXtProt AC: NX_Q3SXY7

Human Synonyms: CSNB1F, FIGLER4

Human Chr (Location): 4q25; chr4:109848184-109872315 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human LRIT3

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from APF )
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (12)    Tissues (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
cDNA source data(1)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase lrit3 ; ZFIN lrit3b    NEW 
Molecular
reagents
All nucleic(2) cDNA(1) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000045099 (Evidence)
Ensembl Gene Model ENSMUSG00000093865 (Evidence)
Entrez Gene 242235 (Evidence)
UniGene 302549
DoTS DT.94125679
NIA Mouse Gene Index U277347
Consensus CDS Project CCDS57256.2
International Mouse Phenotyping Consortium Status Lrit3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045099 VEGA Gene Model | MGI Sequence Detail 16150 C57BL/6J ±  kb
transcript OTTMUST00000118505 VEGA | MGI Sequence Detail 2456 Not Applicable 
polypeptide OTTMUSP00000066145 VEGA | MGI Sequence Detail 681 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(5) UniProt(2)
Polymorphisms
SNPs within 2kb(243 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
InterPro IPR003961 Fibronectin type III
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat N-terminal domain
InterPro IPR003591 Leucine-rich repeat, typical subtype
References
(Earliest) J:143398 Homma S, et al., Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Gene Expr Patterns. 2009 Jan;9(1):1-26
(Latest) J:214644 Neuille M, et al., Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB). PLoS One. 2014;9(3):e90342
All references(16)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory