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Mir195a Gene Detail
Summary
  • Symbol
    Mir195a
  • Name
    microRNA 195a
  • Synonyms
    Mirn195, mmu-mir-195, mmu-mir-195a
Location &
Maps
more
  • Sequence Map
    Chr11:70125868-70125961 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676859
miRNA gene Chr11:70125868-70125961 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007831
miRNA gene Chr11:70755582-70755675 (+)
A/J MGP_AJ_G0007827
miRNA gene Chr11:68066897-68066990 (+)
AKR/J MGP_AKRJ_G0007801
miRNA gene Chr11:70097381-70097474 (+)
BALB/cJ MGP_BALBcJ_G0007804
miRNA gene Chr11:68389672-68389765 (+)
C3H/HeJ MGP_C3HHeJ_G0007751
miRNA gene Chr11:70135743-70135836 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007982
miRNA gene Chr11:72853683-72853776 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007127
miRNA gene Chr11:64985421-64985514 (+)
CAST/EiJ MGP_CASTEiJ_G0007644
miRNA gene Chr11:70381364-70381457 (+)
CBA/J MGP_CBAJ_G0007722
miRNA gene Chr11:76164041-76164134 (+)
DBA/2J MGP_DBA2J_G0007758
miRNA gene Chr11:67642657-67642750 (+)
FVB/NJ MGP_FVBNJ_G0007775
miRNA gene Chr11:67298147-67298240 (+)
LP/J MGP_LPJ_G0007835
miRNA gene Chr11:71325280-71325373 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007745
miRNA gene Chr11:76732204-76732297 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007980
miRNA gene Chr11:70369177-70369270 (+)
PWK/PhJ MGP_PWKPhJ_G0007573
miRNA gene Chr11:68296607-68296700 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007469
miRNA gene Chr11:70167065-70167158 (+)
WSB/EiJ MGP_WSBEiJ_G0007712
miRNA gene Chr11:70032611-70032704 (+)



Homology
more
  • Human Ortholog
    MIR195, microRNA 195
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR195, microRNA 195
  • Synonyms
    mir-195, MIRN195, miRNA195
  • Links
    NCBI Gene ID: 406971

  • Chr Location
    chr17:7017615-7017701 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    9 phenotype references
Homozygous inactivation of this gene results in increased blood-brain barrier permeability.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387190 NCBI Gene Model | MGI Sequence Detail 94 C57BL/6J ±  kb
transcript NR_029581 RefSeq | MGI Sequence Detail 94 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    Primer pair 2
    Other 2
Other Database
Links
less
References
more
  • Summaries
    All 38
    Developmental Gene Expression 8
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:297580 Chen CY, et al., miR-195 reduces age-related blood-brain barrier leakage caused by thrombospondin-1-mediated selective autophagy. Aging Cell. 2020 Nov;19(11):e13236

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory