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Mir155 Gene Detail
Summary
  • Symbol
    Mir155
  • Name
    microRNA 155
  • Synonyms
    Mirn155, mmu-mir-155
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676840
    NCBI Gene: 387173
Location & Maps
more
  • Sequence Map
    Chr16:84714140-84714204 bp, + strand
  • From miRBase annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      65 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 46.92 cM
  • Mapping Data
    1 experiment
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    66 phenotypes from 9 alleles in 10 genetic backgrounds
    3 images
    70 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    14
  • Targeted
    11
  • Transgenic
    3
  • Genomic Mutations
    3 involving Mir155
Mice homozygous for this loss-of-function/reporter allele are viable and fertile, with the lacZ reporter allowing detection of bic/Mirn155 promoter transcriptional activity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 387173 NCBI Gene Model | MGI Sequence Detail 65 C57BL/6J ±  kb
transcript NR_029565 RefSeq | MGI Sequence Detail 65 C57BL/6  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    43 from dbSNP Build 142
Molecular
Reagents
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  • All nucleic 4
    cDNA 2
    Other 2

    Microarray probesets 1
Other Database
Links
less
References
more
  • Summaries
    All 115
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 6
    Phenotypes 70
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:233835 Velazquez KT, et al., MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15;310(6):G347-58

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory