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Prss35 Gene Detail
Summary
  • Symbol
    Prss35
  • Name
    protease, serine 35
  • Synonyms
    6030424L22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444800
    NCBI Gene: 244954
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:86743649-86758443 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 46.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444800
protein coding gene Chr9:86743240-86758443 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035099
protein coding gene Chr9:87596059-87611269 (+)
A/J MGP_AJ_G0035080
protein coding gene Chr9:84533257-84548337 (+)
AKR/J MGP_AKRJ_G0035008
protein coding gene Chr9:86542362-86558813 (+)
BALB/cJ MGP_BALBcJ_G0035068
protein coding gene Chr9:84175022-84191357 (+)
C3H/HeJ MGP_C3HHeJ_G0034780
protein coding gene Chr9:87001514-87017943 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035592
protein coding gene Chr9:89954743-89973861 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032499
protein coding gene Chr9:83317550-83319679 (+)
CAST/EiJ MGP_CASTEiJ_G0034098
protein coding gene Chr9:87464994-87479442 (+)
CBA/J MGP_CBAJ_G0034753
protein coding gene Chr9:93117490-93131949 (+)
DBA/2J MGP_DBA2J_G0034911
protein coding gene Chr9:84091831-84106850 (+)
FVB/NJ MGP_FVBNJ_G0034854
protein coding gene Chr9:83175541-83190741 (+)
LP/J MGP_LPJ_G0034992
protein coding gene Chr9:87806668-87823881 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034896
protein coding gene Chr9:94738512-94753275 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035612
protein coding gene Chr9:86645342-86665482 (+)
PWK/PhJ MGP_PWKPhJ_G0033802
protein coding gene Chr9:84258751-84273589 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033638
protein coding gene Chr9:86846699-86864178 (+)
WSB/EiJ MGP_WSBEiJ_G0034215
protein coding gene Chr9:86685561-86700900 (+)



Homology
more
  • Human Ortholog
    PRSS35, serine protease 35
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PRSS35, serine protease 35
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf158, dJ223E3.1
  • Links
    NCBI Gene ID: 167681
    neXtProt AC: NX_Q8N3Z0
    UniProt: Q8N3Z0

  • Chr Location
    6q14.2; chr6:83512475-83525704 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17734
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PRSS35
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Homozygous null mice exhibit no detectable abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033491 Ensembl Gene Model | MGI Sequence Detail 14795 C57BL/6J ±  kb
transcript ENSMUST00000036426 Ensembl | MGI Sequence Detail 3444 Not Applicable  
polypeptide ENSMUSP00000035271 Ensembl | MGI Sequence Detail 409 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:282576 Nakajima K, et al., Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice. Dis Model Mech. 2019 Nov 12;12(11)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory