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Ccdc174 Gene Detail
Summary
  • Symbol
    Ccdc174
  • Name
    coiled-coil domain containing 174
  • Synonyms
    C130022K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444652
    NCBI Gene: 232236
Location & Maps
more
  • Sequence Map
    Chr6:91878053-91899843 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21791 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 40.90 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CCDC174, coiled-coil domain containing 174
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCDC174, coiled-coil domain containing 174
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C3orf19, HSPC212, IHPM, IHPMR
  • Links
    NCBI Gene ID: 51244
    neXtProt AC: NX_Q6PII3

  • Chr Location
    3p25.1; chr3:14651746-14672659 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CCDC174 associations

Human Disease Mouse Models
       Hypotonia, Infantile, with Psychomotor Retardation; IHPMR   OMIM: 616816
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    3
  • Spontaneous
    1
  • Transgenic
    1
  • Genomic Mutations
    1 involving Ccdc174
  • Incidental Mutations
    APF
Mice homozygous for a transgenic gene disruption may exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023753 VEGA Gene Model | MGI Sequence Detail 21791 C57BL/6J ±  kb
transcript OTTMUST00000058028 VEGA | MGI Sequence Detail 1752 Not Applicable  
polypeptide OTTMUSP00000028063 VEGA | MGI Sequence Detail 467 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    203 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR025066 Protein of unknown function DUF4078
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 4
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory