Brip1
Gene Detail

Symbol Name ID

Brip1 BRCA1 interacting protein C-terminal helicase 1 MGI:2442836

Synonyms

3110009N10Rik, 8030460J03Rik, BACH1

Feature Type

protein coding gene

Genetic Map

Chromosome 11

51.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr11:86058138-86201193 bp, - strand From VEGA annotation of GRCm38   143056 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32766  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Brip1

Human homologs

Human Homolog		BRIP1, BRCA1 interacting protein C-terminal helicase 1
NCBI Gene ID		83990
neXtProt AC		NX_Q9BX63
Human Synonyms		BACH1, FANCJ, OF
Human Chr (Location)		17q22.2; chr17:59756547-59940920 (-)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human BRIP1

Alleles and phenotypes

All alleles(5) : Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	DNA repair, negative regulation of cell proliferation, ...
Component	cytoplasm, nuclear membrane, ...
Function	4 iron, 4 sulfur cluster binding, ATP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (87)    Tissues (8)    Images (23)
Theiler Stages: 23

Assay Type	Results
RNA in situ	87

cDNA source data(29)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(29) cDNA(29)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000001045 (Evidence)
Ensembl Gene Model	ENSMUSG00000034329 (Evidence)
Entrez Gene	237911 (Evidence)
UniGene	186143
DFCI	TC1581686, TC1661246
DoTS	DT.110522724, DT.91336630, DT.94225707
NIA Mouse Gene Index	U033218
EC	3.6.4.13
Consensus CDS Project	CCDS25197.1
International Mouse Knockout Project Status	Brip1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000001045	VEGA Gene Model | MGI Sequence Detail	143056	C57BL/6J
transcript	OTTMUST00000002085	VEGA | MGI Sequence Detail	6931	Not Applicable
polypeptide	OTTMUSP00000001009	VEGA | MGI Sequence Detail	1174	Not Applicable

All sequences(36) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(209 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006555	ATP-dependent helicase, C-terminal
InterPro	IPR010614	DEAD2
InterPro	IPR013020	DNA helicase (DNA repair), Rad3 type
InterPro	IPR014001	Helicase, superfamily 1/2, ATP-binding domain
InterPro	IPR014013	Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type
Protein Ontology	PR:000004816	Fanconi anemia group J protein

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Other accession IDs

MGI:1920358