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Naa25 Gene Detail
Summary
  • Symbol
    Naa25
  • Name
    N(alpha)-acetyltransferase 25, NatB auxiliary subunit
  • Synonyms
    4833422K13Rik, C330023M02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442563
    NCBI Gene: 231713
Location & Maps
more
  • Sequence Map
    Chr5:121397936-121444378 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      46443 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 61.79 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NAA25, N(alpha)-acetyltransferase 25, NatB auxiliary subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NAA25, N(alpha)-acetyltransferase 25, NatB auxiliary subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C12orf30, MDM20, NAP1
  • Links
    NCBI Gene ID: 80018
    neXtProt AC: NX_Q14CX7

  • Chr Location
    12q24.13; chr12:112026689-112109022 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6891
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NAA25
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    55
  • Chemically induced (other)
    1
  • Gene trapped
    51
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Naa25
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026322 VEGA Gene Model | MGI Sequence Detail 46443 C57BL/6J ±  kb
transcript OTTMUST00000065105 VEGA | MGI Sequence Detail 5447 Not Applicable  
polypeptide OTTMUSP00000032404 VEGA | MGI Sequence Detail 972 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    141 from dbSNP Build 142
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000030793 N-alpha-acetyltransferase 25, NatB auxiliary subunit
  • InterPro Domains
    IPR019183 N-acetyltransferase B complex, non-catalytic subunit
    IPR011990 Tetratricopeptide-like helical domain
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 5
Other
Accession IDs
less
MGI:1918880, MGI:2140896
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:180596 Ohyama K, et al., Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain: Implications for co-operative versus non-co-operative actions of Mdm20 and Nat5. Gene Expr Patterns. 2012 Jan;12(1-2):36-45

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory