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Naa25 Gene Detail
Summary
  • Symbol
    Naa25
  • Name
    N(alpha)-acetyltransferase 25, NatB auxiliary subunit
  • Synonyms
    4833422K13Rik, C330023M02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442563
    NCBI Gene: 231713
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:121535977-121580612 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 61.79 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442563
protein coding gene Chr5:121535977-121582441 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030026
protein coding gene Chr5:124875403-124929360 (+)
A/J MGP_AJ_G0029991
protein coding gene Chr5:119739039-119786181 (+)
AKR/J MGP_AKRJ_G0029928
protein coding gene Chr5:123614792-123661513 (+)
BALB/cJ MGP_BALBcJ_G0030002
protein coding gene Chr5:121122747-121169745 (+)
C3H/HeJ MGP_C3HHeJ_G0029720
protein coding gene Chr5:124176409-124225806 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030455
protein coding gene Chr5:129641792-129688649 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027681
protein coding gene Chr5:114418301-114466911 (+)
CAST/EiJ MGP_CASTEiJ_G0029128
protein coding gene Chr5:123289635-123338248 (+)
CBA/J MGP_CBAJ_G0029689
protein coding gene Chr5:134730882-134786333 (+)
DBA/2J MGP_DBA2J_G0029839
protein coding gene Chr5:119810928-119857357 (+)
FVB/NJ MGP_FVBNJ_G0029796
protein coding gene Chr5:118758736-118805373 (+)
LP/J MGP_LPJ_G0029928
protein coding gene Chr5:125397380-125447263 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029826
protein coding gene Chr5:138598450-138645883 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030496
protein coding gene Chr5:123123784-123176799 (+)
PWK/PhJ MGP_PWKPhJ_G0028842
protein coding gene Chr5:118579631-118627755 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028679
protein coding gene Chr5:120887552-120941985 (+)
WSB/EiJ MGP_WSBEiJ_G0029203
protein coding gene Chr5:123783780-123832577 (+)



Homology
more
  • Human Ortholog
    NAA25, N-alpha-acetyltransferase 25, NatB auxiliary subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NAA25, N-alpha-acetyltransferase 25, NatB auxiliary subunit
  • Synonyms
    C12orf30, MDM20, NAP1
  • Links
    NCBI Gene ID: 80018
    neXtProt AC: NX_Q14CX7
    UniProt: Q14CX7

  • Chr Location
    12q24.13; chr12:112026689-112109022 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 231713 NCBI Gene Model | MGI Sequence Detail 44636 C57BL/6J ±  kb
    transcript NM_172722 RefSeq | MGI Sequence Detail 5402 C57BL/6  
    polypeptide Q8BWZ3 UniProt | EBI | MGI Sequence Detail 972 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • Protein Ontology
      PR:000030793 N-alpha-acetyltransferase 25, NatB auxiliary subunit
    • InterPro Domains
      IPR019183 N-acetyltransferase B complex, non-catalytic subunit
      IPR011990 Tetratricopeptide-like helical domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 27
      cDNA 27

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1918880, MGI:2140896
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 18
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:306784 Alves S, et al., N-terminal acetylation modulates Bax targeting to mitochondria. Int J Biochem Cell Biol. 2018 Feb;95:35-42

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    01/18/2022
    MGI 6.17
    The Jackson Laboratory