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B9d2 Gene Detail
Summary
  • Symbol
    B9d2
  • Name
    B9 protein domain 2
  • Synonyms
    MGC:41256, stumpy
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387643
    NCBI Gene: 232987
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25680780-25686558 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 13.97 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387643
protein coding gene Chr7:25679671-25686562 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031875
protein coding gene Chr7:24188592-24194369 (+)
A/J MGP_AJ_G0031854
protein coding gene Chr7:23552882-23561619 (+)
AKR/J MGP_AKRJ_G0031783
protein coding gene Chr7:24159568-24165346 (+)
BALB/cJ MGP_BALBcJ_G0031859
protein coding gene Chr7:23795047-23800832 (+)
C3H/HeJ MGP_C3HHeJ_G0031580
protein coding gene Chr7:24570580-24577743 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032323
protein coding gene Chr7:25002362-25009617 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029378
protein coding gene Chr7:24894889-24900905 (+)
CAST/EiJ MGP_CASTEiJ_G0030920
protein coding gene Chr7:17984289-17990219 (+)
CBA/J MGP_CBAJ_G0031545
protein coding gene Chr7:25877486-25886000 (+)
DBA/2J MGP_DBA2J_G0031699
protein coding gene Chr7:23449920-23455714 (+)
FVB/NJ MGP_FVBNJ_G0031652
protein coding gene Chr7:23481072-23487151 (+)
LP/J MGP_LPJ_G0031778
protein coding gene Chr7:24466207-24471979 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031689
protein coding gene Chr7:25610745-25616565 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032355
protein coding gene Chr7:23800092-23805873 (+)
PWK/PhJ MGP_PWKPhJ_G0030644
protein coding gene Chr7:18400510-18406369 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030474
protein coding gene Chr7:15124002-15131357 (+)
WSB/EiJ MGP_WSBEiJ_G0031023
protein coding gene Chr7:24019437-24025217 (+)



Homology
more
  • Human Ortholog
    B9D2, B9 domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    B9D2, B9 domain containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ICIS-1, JBTS34, MKS10, MKSR2, MKSR-2
  • Links
    NCBI Gene ID: 80776
    neXtProt AC: NX_Q9BPU9
    UniProt: Q9BPU9

  • Chr Location
    19q13.2; chr19:41354417-41364540 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12733
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: B9D2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    116 phenotypes from 2 alleles in 6 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice carrying a targeted mutation of this gene exhibit preweaning lethality, hydrops fetalis, and abnormalities in craniofacial, limb, and eye development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063439 Ensembl Gene Model | MGI Sequence Detail 5779 C57BL/6J ±  kb
transcript ENSMUST00000108403 Ensembl | MGI Sequence Detail 1021 Not Applicable  
polypeptide ENSMUSP00000104040 Ensembl | MGI Sequence Detail 175 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 19
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:246794 Edwards JP, et al., The GARP/Latent TGF-beta1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance. Eur J Immunol. 2016 Jun;46(6):1480-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory