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Ppat
Gene Detail
 Symbol
Name
ID
Ppat
phosphoribosyl pyrophosphate amidotransferase
MGI:2387203
Synonyms 5730454C12Rik, MGC:38417
Feature Type protein coding gene
Genetic Map
Chromosome 5
41.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:76913249-76951578 bp, - strand
From VEGA annotation of GRCm38

  38330 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68272  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Amd_phspho_trans
Gene Tree: Ppat

Human
homologs
Human Homolog PPAT, phosphoribosyl pyrophosphate amidotransferase
NCBI Gene ID 5471
neXtProt AC  NX_Q06203
Human Synonyms  ATASE, GPAT, PRAT
Human Chr (Location)  4q12; chr4:56393362-56435636 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(22) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ppat interacts with 343 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process glutamine catabolic process, protein homotetramerization, ...
Function amidophosphoribosyltransferase activity, iron-sulfur cluster binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (202)    Tissues (104)    Images (29)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 202
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000026529 (Evidence)
Ensembl Gene ModelENSMUSG00000029246 (Evidence)
Entrez Gene231327 (Evidence)
DFCITC1575948, TC1623105, TC1658311
NIA Mouse Gene IndexU026328
EC2.4.2.14
Consensus CDS ProjectCCDS51527.1
International Mouse Knockout Project StatusPpat
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026529 VEGA Gene Model | MGI Sequence Detail 38330 C57BL/6J ±  kb
transcript OTTMUST00000065636 VEGA | MGI Sequence Detail 3981 Not Applicable 
polypeptide OTTMUSP00000032738 VEGA | MGI Sequence Detail 517 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(2) UniProt(6)
Polymorphisms SNPs within 2kb(297 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005854 Amidophosphoribosyl transferase
InterPro IPR000583 Class II glutamine amidotransferase domain
InterPro IPR017932 Glutamine amidotransferase type 2 domain
InterPro IPR000836 Phosphoribosyltransferase domain
Protein Ontology PR:000013061 amidophosphoribosyltransferase
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)
Other
accession IDs
MGI:1917832, MGI:2140739, MGI:2140788, MGI:2140930, MGI:2141313

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory