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Gy
Other Genome Feature Detail
Symbol

Name
ID
Gy
gyro deletion region
MGI:2180716
Feature Type
unclassified other genome feature
Genetic Map
Chromosome X
Syntenic

Mapping data(6)
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Radiation induced(1)
 
Hemizygous males for an irradiation-induced X-linked deletion that disrupts both Sms and Phex genes show the hypophosphatemic rickets (found also in mice with lone Phex mutations) but also exhibit reduced viability, circling behavior, markedly reduced spermine content, and sterility.
 
Human Diseases Modeled Using Mouse Gy (1)    Alleles Annotated to Human Diseases(1)   
Other database
links
Entrez Gene246722
References
(Earliest) J:28887 Carter TC, et al., The genetic sensitivity to X-rays of mouse foetal gonads. Genet Res. 1960;1:351-5
(Latest) J:145570 Wang X, et al., Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine. J Biol Chem. 2009 Jan 9;284(2):930-7
All references(27)
Disease annotation references (2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory