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Cdk20 Gene Detail
Summary
  • Symbol
    Cdk20
  • Name
    cyclin-dependent kinase 20
  • Synonyms
    4932702G04Rik, Ccrk
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145349
    NCBI Gene: 105278
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr13:64432319-64439722 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7404 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 33.26 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CDK20, cyclin dependent kinase 20
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CDK20, cyclin dependent kinase 20
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CCRK, CDCH, P42, PNQALRE
  • Links
    NCBI Gene ID: 23552
    neXtProt AC: NX_Q8IZL9
    UniProt: Q8IZL9

  • Chr Location
    9q22.1; chr9:87966441-87974780 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display exencephaly, open neural tubes, cleft palate, absence of the floor plate, achondroplasia of the radius and ulna, and abnormal cilia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 105278 NCBI Gene Model | MGI Sequence Detail 7404 C57BL/6J ±  kb
    transcript NM_053180 RefSeq | MGI Sequence Detail 1854 Not Specified  
    polypeptide Q9JHU3 UniProt | EBI | MGI Sequence Detail 346 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      138 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 38

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2145459
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:257916 Lupu FI, et al., Cell cycle-related kinase regulates mammalian eye development through positive and negative regulation of the Hedgehog pathway. Dev Biol. 2018 Feb 1;434(1):24-35

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    09/18/2018
    MGI 6.12
    The Jackson Laboratory