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Tug1 Gene Detail
Summary
  • Symbol
    Tug1
  • Name
    taurine upregulated gene 1
  • Feature Type
    unclassified non-coding RNA gene
  • IDs
    MGI:2144114
    NCBI Gene: 544752
  • Gene Overview
    MyGene.info: TUG1
  • Alliance
Location & Maps
more
  • Genetic Map
    Chromosome 11, 2.56 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TUG1, taurine up-regulated 1 (non-protein coding)
  • Human Ortholog
    TUG1, taurine up-regulated 1 (non-protein coding)
    Orthology source: HGNC
  • Synonyms
    LINC00080, NCRNA00080, TI-227H
  • Links
    NCBI Gene ID: 55000

  • Chr Location
    22q12.2; chr22:30969211-30979395 (+)  GRCh38.p7

  • HCOP
    human homology predictions: TUG1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a null allele are viable.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005033 VEGA Gene Model | MGI Sequence Detail 9889 C57BL/6J ±  kb
transcript OTTMUST00000011198 VEGA | MGI Sequence Detail 6709 Not Applicable  
polypeptide Q8CI88 UniProt | EBI | MGI Sequence Detail 82 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    10 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
Molecular
Reagents
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  • All nucleic 21
    cDNA 21

    Microarray probesets 8
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:31358 Ishiguro T, et al., Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials. Cancer Res. 1996 Feb 15;56(4):875-9
  • Latest
    J:239614 Long J, et al., Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy. J Clin Invest. 2016 Nov 01;126(11):4205-4218

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory