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Tug1 Gene Detail
Summary
  • Symbol
    Tug1
  • Name
    taurine upregulated gene 1
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2144114
    NCBI Gene: 544752
  • Gene Overview
    MyGene.info: TUG1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3639785-3648814 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 2.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144114
lncRNA gene Chr11:3639785-3649673 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015150
unclassified non-coding RNA gene Chr11:526716-537444 (-)
A/J MGP_AJ_G0015124
unclassified non-coding RNA gene Chr11:564011-574549 (-)
AKR/J MGP_AKRJ_G0015087
unclassified non-coding RNA gene Chr11:584436-595678 (-)
BALB/cJ MGP_BALBcJ_G0015087
unclassified non-coding RNA gene Chr11:530755-541892 (-)
C3H/HeJ MGP_C3HHeJ_G0014910
unclassified non-coding RNA gene Chr11:517213-527088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0015543
unclassified non-coding RNA gene Chr11:601339-613134 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013289
unclassified non-coding RNA gene Chr11:467448-477405 (-)
CAST/EiJ MGP_CASTEiJ_G0014464
unclassified non-coding RNA gene Chr11:482558-492462 (-)
CBA/J MGP_CBAJ_G0014889
unclassified non-coding RNA gene Chr11:774772-785913 (-)
DBA/2J MGP_DBA2J_G0014982
unclassified non-coding RNA gene Chr11:477641-488077 (-)
FVB/NJ MGP_FVBNJ_G0014993
unclassified non-coding RNA gene Chr11:508894-518770 (-)
LP/J MGP_LPJ_G0015064
unclassified non-coding RNA gene Chr11:616781-626194 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015020
unclassified non-coding RNA gene Chr11:524124-533911 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0015582
unclassified non-coding RNA gene Chr11:599032-609791 (-)
PWK/PhJ MGP_PWKPhJ_G0014256
unclassified non-coding RNA gene Chr11:465095-475053 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014044
unclassified non-coding RNA gene Chr11:555797-565665 (-)
WSB/EiJ MGP_WSBEiJ_G0014567
unclassified non-coding RNA gene Chr11:475604-485604 (-)



Homology
more
  • Human Ortholog
    TUG1, taurine up-regulated 1
  • Human Ortholog
    TUG1, taurine up-regulated 1
    Orthology source: HGNC
  • Synonyms
    LINC00080, NCRNA00080, TI-227H
  • Links
    NCBI Gene ID: 55000

  • Chr Location
    22q12.2; chr22:30969211-30979395 (+)  GRCh38.p7

  • HCOP
    human homology predictions: TUG1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a null allele are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 544752 NCBI Gene Model | MGI Sequence Detail 9030 C57BL/6J ±  kb
transcript NR_002322 RefSeq | MGI Sequence Detail 6719 C57BL/6  
polypeptide Q8CI88 UniProt | EBI | MGI Sequence Detail 82 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 8
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:31358 Ishiguro T, et al., Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials. Cancer Res. 1996 Feb 15;56(4):875-9
  • Latest
    J:248986 Su S, et al., Overexpression of the long noncoding RNA TUG1 protects against cold-induced injury of mouse livers by inhibiting apoptosis and inflammation. FEBS J. 2016 Apr;283(7):1261-74

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory