About   Help   FAQ
B3gnt5 Gene Detail
Summary
  • Symbol
    B3gnt5
  • Name
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137302
    NCBI Gene: 108105
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr16:19760208-19772463 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12256 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 12.23 cM, cytoband B1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    B3GNT5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    B3GNT5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B3GN-T5, beta3Gn-T5
  • Links
    NCBI Gene ID: 84002
    neXtProt AC: NX_Q9BYG0
    UniProt: Q9BYG0

  • Chr Location
    3q27.1; chr3:183253207-183273391 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 24989
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: B3GNT5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 4 alleles in 4 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice may show variable types of lethality or no lethality depending on the allele. Mice homozygous for 3 alleles show B cell abnormalities. Mice homozygous or heterozygous for 2 allele show reduced fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000026282 VEGA Gene Model | MGI Sequence Detail 12256 C57BL/6J ±  kb
    transcript OTTMUST00000065001 VEGA | MGI Sequence Detail 2229 Not Applicable  
    polypeptide OTTMUSP00000032339 VEGA | MGI Sequence Detail 376 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      130 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 75
      cDNA 74
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:70124 Togayachi A, et al., Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids. J Biol Chem. 2001 Jun 22;276(25):22032-40
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    10/09/2018
    MGI 6.12
    The Jackson Laboratory