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B3gnt5
Gene Detail
 Symbol
Name
ID
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
MGI:2137302
Feature Type protein coding gene
Genetic Map
Chromosome 16
12.23 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:19760208-19772463 bp, + strand
From VEGA annotation of GRCm38

  12256 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:24989  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: B3gnt5

Human
homologs
Human Homolog B3GNT5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
NCBI Gene ID 84002
neXtProt AC  NX_Q9BYG0
Human Synonyms  B3GN-T5, beta3Gn-T5
Human Chr (Location)  3q28; chr3:183253244-183273391 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(4) Targeted(8)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice may show variable types of lethality or no lethality depending on the allele. Mice homozygous for 3 alleles show B cell abnormalities. Mice homozygous or heterozygous for 2 allele show reduced fertility.
 
Interactions
B3gnt5 interacts with 335 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process central nervous system development, lipopolysaccharide biosynthetic process, ...
Component Golgi apparatus, integral component of membrane, ...
Function beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity, galactosyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (130)    Tissues (126)    Images (15)
Theiler Stages: 2, 5, 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 116
Northern blot 14
cDNA source data(73)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) cDNA(73) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026282 (Evidence)
Ensembl Gene ModelENSMUSG00000022686 (Evidence)
Entrez Gene108105 (Evidence)
UniGene33935
DFCITC1578293, TC1611287, TC1665156
DoTSDT.101382186, DT.103557833, DT.485221, DT.94122922, DT.97397284
NIA Mouse Gene IndexU043503
EC2.4.1.206
Consensus CDS ProjectCCDS28040.1
International Mouse Knockout Project StatusB3gnt5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026282 VEGA Gene Model | MGI Sequence Detail 12256 C57BL/6J ±  kb
transcript OTTMUST00000064999 VEGA | MGI Sequence Detail 4175 Not Applicable 
polypeptide OTTMUSP00000032338 VEGA | MGI Sequence Detail 376 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002659 Glycosyl transferase, family 31
Protein Ontology PR:000004595 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
References (Earliest) J:70124 Togayachi A, et al., Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids. J Biol Chem. 2001 Jun 22;276(25):22032-40
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory