Tg(WapNotch4)10Rnc
Transgene Detail
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Symbol: |
Tg(WapNotch4)10Rnc |
Name: |
transgene insertion 10, Robert Callahan |
MGI ID: |
MGI:1930202 |
Synonyms: |
Tg(WapInt3)10Rnc, WAP/Int3, Wap-int3 tg |
Transgene: |
Tg(WapNotch4)10Rnc Location: unknown Genetic Position: ChrX, Syntenic
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Alliance: |
Tg(WapNotch4)10Rnc page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(WapNotch4)10Rnc expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
rat |
Notch4 (406162) |
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Mutation details: The transgene insert consisted of the mouse whey acidic acid promoter and the portion of the Notch4 gene encoding the intracellular domain. Wap promoter activity is restricted to the secretory mammary epithelial population. Four founder mice were identified. One line established from founder 10. Transmission analysis indicates that the transgene inserted into the X chromosome.
(J:33193)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:33193 Gallahan D, et al., Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res. 1996 Apr 15;56(8):1775-85 |
All: |
12 reference(s) |
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