Naa35 Gene Detail

Summary

• Symbol
  Naa35
• Name
  N(alpha)-acetyltransferase 35, NatC auxiliary subunit
• Synonyms
  A330021G12Rik, A330027C19Rik, C030004C14Rik, Mak10

• Feature Type
  protein coding gene
• IDs
  MGI:1925939
  NCBI Gene: 78689
• Gene Overview
  MyGene.info: NAA35
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr13:59585323-59634798 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, 31.87 cM, cytoband B3
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  425 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925939	protein coding gene	Chr13:59585259-59635922 (.)
129S1/SvImJ	MGP_129S1SvImJ_G0020638	protein coding gene	Chr13:59294298-59343285 (+)
A/J	MGP_AJ_G0020592	protein coding gene	Chr13:57077708-57127536 (+)
AKR/J	MGP_AKRJ_G0020570	protein coding gene	Chr13:58784217-58835498 (+)
BALB/cJ	MGP_BALBcJ_G0020588	protein coding gene	Chr13:57338470-57387760 (+)
C3H/HeJ	MGP_C3HHeJ_G0020387	protein coding gene	Chr13:58578180-58627676 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021022	protein coding gene	Chr13:61083835-61133272 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018604	protein coding gene	Chr13:54967726-55019440 (+)
CAST/EiJ	MGP_CASTEiJ_G0019903	protein coding gene	Chr13:58782820-58831910 (+)
CBA/J	MGP_CBAJ_G0020347	protein coding gene	Chr13:63395137-63444366 (+)
DBA/2J	MGP_DBA2J_G0020470	protein coding gene	Chr13:56624739-56674342 (+)
FVB/NJ	MGP_FVBNJ_G0020449	protein coding gene	Chr13:56105553-56155610 (+)
LP/J	MGP_LPJ_G0020546	protein coding gene	Chr13:59553764-59603866 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020478	protein coding gene	Chr13:62699630-62749127 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021065	protein coding gene	Chr13:58388041-58438713 (+)
PWK/PhJ	MGP_PWKPhJ_G0019657	protein coding gene	Chr13:56648559-56699205 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019484	protein coding gene	Chr13:57269426-57322061 (+)
WSB/EiJ	MGP_WSBEiJ_G0019963	protein coding gene	Chr13:58834795-58885894 (+)

Homology

• Human Ortholog
  NAA35, N(alpha)-acetyltransferase 35, NatC auxiliary subunit

• Vertebrate Orthologs
  10

• Human Ortholog
  NAA35, N(alpha)-acetyltransferase 35, NatC auxiliary subunit
  Orthology source: HomoloGene, HGNC
• Synonyms
  bA379P1.1, EGAP, MAK10, MAK10P
• Links
  HGNC:24340

  NCBI Gene ID: 60560

  neXtProt AC: NX_Q5VZE5

  UniProt: Q5VZE5

  
  
• Chr Location
  9q21.33; chr9:85941142-86026355 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 5781
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: NAA35
• Gene Tree
  Naa35
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  12 phenotype references
  

• All Mutations and Alleles
  64
• Chemically induced (other)
  1
• Gene trapped
  59
• Targeted
  4
• Genomic Mutations
  1 involving Naa35
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  26 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  14
• GO References
  5

• External Resources
  FuncBase

Expression

• Assay Results
  1
• Tissues
  1
• cDNA Data
  139
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase naa35
  ZFIN naa35

Interactions

• Naa35 interacts with 68 markers (Mir17, Mir20a, Mir20b, ...) View All

Sequences &
Gene Models

• All Sequences
  83
• RefSeq
  8
• UniProt
  7
• CCDS
  CCDS26575.1
• UniGene
  253902

• Ensembl
  ENSMUSG00000021555 (Evidence)
• NCBI Gene
  78689

Representative Sequences			Length	Strain/Species
genomic	78689	NCBI Gene Model | MGI Sequence Detail	49476	C57BL/6J
transcript	NM_030153	RefSeq | MGI Sequence Detail	2646	C57BL/6
polypeptide	Q6PHQ8	UniProt | EBI | MGI Sequence Detail	725	Not Applicable

Protein
Information

• UniProt
  7 Sequences
• Protein Ontology
  PR:000010090 protein MAK10
  (term hierarchy)
• InterPro Domains
  IPR007244 NatC N(alpha)-terminal acetyltransferase, Mak10 subunit

Molecular
Reagents

• All nucleic 140

  cDNA 140

  
  

  Microarray probesets 8

Other
Accession IDs

MGI:2145187, MGI:2441791, MGI:2444200

References

• Summaries
  All 38

  Developmental Gene Expression 1

  Gene Ontology 5

  Phenotypes 12
• Earliest
  J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
• Latest
  J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Naa35:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr120097	Chr13:59585301-59585325 (+)	-10 bp
Tssr120098	Chr13:59585348-59585441 (+)	72 bp
Tssr120099	Chr13:59625139-59625165 (+)	39,829 bp