Naa35 MGI Mouse Gene Detail - MGI:1925939 - N(alpha)-acetyltransferase 35, NatC auxiliary subunit

Symbol

Naa35
Name

N(alpha)-acetyltransferase 35, NatC auxiliary subunit
Synonyms

A330021G12Rik, A330027C19Rik, C030004C14Rik, Mak10

Feature Type

protein coding gene
IDs

MGI:1925939
NCBI Gene: 78689
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr13:59733147-59782612 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 31.87 cM, cytoband B3
Mapping Data

3 experiments

SNPs within 2kb

2945 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925939	protein coding gene	Chr13:59733073-59783736 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020638	protein coding gene	Chr13:59294298-59343285 (+)
A/J	MGP_AJ_G0020592	protein coding gene	Chr13:57077708-57127536 (+)
AKR/J	MGP_AKRJ_G0020570	protein coding gene	Chr13:58784217-58835498 (+)
BALB/cJ	MGP_BALBcJ_G0020588	protein coding gene	Chr13:57338470-57387760 (+)
C3H/HeJ	MGP_C3HHeJ_G0020387	protein coding gene	Chr13:58578180-58627676 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021022	protein coding gene	Chr13:61083835-61133272 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018604	protein coding gene	Chr13:54967726-55019440 (+)
CAST/EiJ	MGP_CASTEiJ_G0019903	protein coding gene	Chr13:58782820-58831910 (+)
CBA/J	MGP_CBAJ_G0020347	protein coding gene	Chr13:63395137-63444366 (+)
DBA/2J	MGP_DBA2J_G0020470	protein coding gene	Chr13:56624739-56674342 (+)
FVB/NJ	MGP_FVBNJ_G0020449	protein coding gene	Chr13:56105553-56155610 (+)
LP/J	MGP_LPJ_G0020546	protein coding gene	Chr13:59553764-59603866 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020478	protein coding gene	Chr13:62699630-62749127 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021065	protein coding gene	Chr13:58388041-58438713 (+)
PWK/PhJ	MGP_PWKPhJ_G0019657	protein coding gene	Chr13:56648559-56699205 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019484	protein coding gene	Chr13:57269426-57322061 (+)
WSB/EiJ	MGP_WSBEiJ_G0019963	protein coding gene	Chr13:58834795-58885894 (+)

Human Ortholog

NAA35, N-alpha-acetyltransferase 35, NatC auxiliary subunit

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

NAA35, N-alpha-acetyltransferase 35, NatC auxiliary subunit
Synonyms

bA379P1.1, EGAP, MAK10, MAK10P
Links

HGNC:24340

NCBI Gene ID: 60560

UniProt: Q5VZE5
Chr Location

9q21.33; chr9:85941146-86025462 (+) GRCh38

MGI Vertebrate Homology

Naa35 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: NAA35
Gene Tree

Naa35

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
16 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

46
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

39
Targeted

4
Genomic Mutations

1 involving Naa35
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

59 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

22
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

707
Tissues

1
cDNA Data

139
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase naa35

ZFIN naa35

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All Sequences

88
RefSeq

13
UniProt

7
CCDS

CCDS26575.1

Ensembl

ENSMUSG00000021555 (Evidence)
NCBI Gene

78689

			Length	Strain/Species	Flank
genomic	78689	NCBI Gene Model \| MGI Sequence Detail	49466	C57BL/6J	± kb
transcript	NM_001384120	RefSeq \| MGI Sequence Detail	2879	C57BL/6
polypeptide	Q6PHQ8	UniProt \| EBI \| MGI Sequence Detail	725	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000010090 protein MAK10

(term hierarchy)
InterPro Domains

IPR007244 -alpha-acetyltransferase 35, NatC auxiliary subunit
GlyGen

Q6PHQ8 1 site, 1 N-linked glycan (1 site)

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All nucleic 140

cDNA 140

Microarray probesets 8

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MGI:2145187, MGI:2441791, MGI:2444200

Summaries

All 45

Developmental Gene Expression 1

Gene Ontology 8

Phenotypes 16
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Naa35:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr120097	Chr13:59733115-59733139 (+)	-20 bp
Tssr120098	Chr13:59733162-59733255 (+)	62 bp
Tssr120099	Chr13:59772953-59772979 (+)	39,819 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24