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Ascc3 Gene Detail
Summary
  • Symbol
    Ascc3
  • Name
    activating signal cointegrator 1 complex subunit 3
  • Synonyms
    ASC1p200, B630009I04Rik, Helic1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925237
    NCBI Gene: 77987
  • Gene Overview
    MyGene.info: ASCC3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:50592669-50851202 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 24.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925237
protein coding gene Chr10:50592669-50851485 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017212
protein coding gene Chr10:49661810-49944870 (+)
A/J MGP_AJ_G0017188
protein coding gene Chr10:48189247-48453333 (+)
AKR/J MGP_AKRJ_G0017147
protein coding gene Chr10:49114155-49372162 (+)
BALB/cJ MGP_BALBcJ_G0017149
protein coding gene Chr10:48341302-48603216 (+)
C3H/HeJ MGP_C3HHeJ_G0016973
protein coding gene Chr10:49366712-49634863 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017607
protein coding gene Chr10:51228965-51509190 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015302
protein coding gene Chr10:45642571-45911340 (+)
CAST/EiJ MGP_CASTEiJ_G0016547
protein coding gene Chr10:49519543-49794713 (+)
CBA/J MGP_CBAJ_G0016944
protein coding gene Chr10:53500130-53792341 (+)
DBA/2J MGP_DBA2J_G0017049
protein coding gene Chr10:47652525-47911086 (+)
FVB/NJ MGP_FVBNJ_G0017043
protein coding gene Chr10:47020775-47269330 (+)
LP/J MGP_LPJ_G0017124
protein coding gene Chr10:49692610-49980602 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017072
protein coding gene Chr10:55279913-55591970 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017643
protein coding gene Chr10:49075511-49341460 (+)
PWK/PhJ MGP_PWKPhJ_G0016326
protein coding gene Chr10:47492392-47760536 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016111
protein coding gene Chr10:48667555-48946479 (+)
WSB/EiJ MGP_WSBEiJ_G0016610
protein coding gene Chr10:49286673-49556219 (+)



Homology
more
  • Human Ortholog
    ASCC3, activating signal cointegrator 1 complex subunit 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ASCC3, activating signal cointegrator 1 complex subunit 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ASC1p200, HELIC1, RNAH
  • Links
    NCBI Gene ID: 10973
    neXtProt AC: NX_Q8N3C0
    UniProt: Q8N3C0

  • Chr Location
    6q16.3; chr6:100508194-100881372 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77987 NCBI Gene Model | MGI Sequence Detail 258534 C57BL/6J ±  kb
    transcript NM_198007 RefSeq | MGI Sequence Detail 7477 C57BL/6  
    polypeptide E9PZJ8 UniProt | EBI | MGI Sequence Detail 2198 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 59
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:3039633
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:246912 Ye A, et al., PEG3 control on the mammalian MSL complex. PLoS One. 2017;12(6):e0178363

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory