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Ascc3
Gene Detail
 Symbol
Name
ID
Ascc3
activating signal cointegrator 1 complex subunit 3
MGI:1925237
Synonyms ASC1p200, B630009I04Rik, Helic1
Feature Type protein coding gene
Genetic Map
Chromosome 10
24.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:50592669-50851202 bp, + strand
From NCBI annotation of GRCm38

  258534 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4973  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ascc3

Human
homologs
Human Homolog ASCC3, activating signal cointegrator 1 complex subunit 3
NCBI Gene ID 10973
neXtProt AC  NX_Q8N3C0
Human Synonyms  ASC1p200, HELIC1, RNAH
Human Chr (Location)  6q16; chr6:100508194-100881372 (-)  GRCh38
Alleles
and
phenotypes
All alleles(16) : Targeted(2) Gene trapped(14)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process ATP catabolic process, cell proliferation, ...
Component cytoplasm, Golgi apparatus, ...
Function ATP binding, ATP-dependent 3'-5' DNA helicase activity, ...
External Resources: FuncBase
Expression
cDNA source data(58)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(58) cDNA(58)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000038774 (Evidence)
Entrez Gene77987 (Evidence)
UniGene222497
DFCITC1582699, TC1603375, TC1606927
DoTSDT.40176271, DT.94222719
NIA Mouse Gene IndexU011495, U364131, U365919
EC3.6.4.12
Consensus CDS ProjectCCDS48555.1
International Mouse Knockout Project StatusAscc3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 77987 NCBI Gene Model | MGI Sequence Detail 258534 C57BL/6J ±  kb
transcript NM_198007 RefSeq | MGI Sequence Detail 7477 C57BL/6 
polypeptide E9PZJ8 UniProt | EBI | MGI Sequence Detail 2198 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(1196 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR004179 Sec63 domain
Protein Ontology PR:000004361 activating signal cointegrator 1 complex subunit 3
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
All references(30)
Other
accession IDs
MGI:3039633

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory