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Elp4 Gene Detail
Summary
  • Symbol
    Elp4
  • Name
    elongator acetyltransferase complex subunit 4
  • Synonyms
    A330107A17Rik, Paxneb
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925016
    NCBI Gene: 77766
  • Gene Overview
    MyGene.info: ELP4
Location & Maps
more
  • Sequence Map
    Chr2:105701027-105904564 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      203538 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 55.33 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ELP4, elongator acetyltransferase complex subunit 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ELP4, elongator acetyltransferase complex subunit 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AN, C11orf19, dJ68P15A.1, hELP4, PAX6NEB, PAXNEB
  • Links
    NCBI Gene ID: 26610
    neXtProt AC: NX_Q96EB1

  • Chr Location
    11p13; chr11:31509729-31785252 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ELP4 associations

Human Disease Mouse Models
       Aniridia; AN   OMIM: 106210
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Spontaneous
    2
  • Targeted
    2
  • Genomic Mutations
    5 involving Elp4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015120 VEGA Gene Model | MGI Sequence Detail 203538 C57BL/6J ±  kb
transcript OTTMUST00000035858 VEGA | MGI Sequence Detail 3048 Not Applicable  
polypeptide OTTMUSP00000016086 VEGA | MGI Sequence Detail 422 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    633 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007045 elongator complex protein 4
  • InterPro Domains
    IPR008728 Elongator complex protein 4
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 15
    cDNA 14
    Other 1

    Microarray probesets 6
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory