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Rin2 Gene Detail
Summary
  • Symbol
    Rin2
  • Name
    Ras and Rab interactor 2
  • Synonyms
    2010003K16Rik, 4632403N06Rik, RASSF4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921280
    NCBI Gene: 74030
  • Alliance
  • Transcription Start Sites
    25 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:145771727-145887616 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 71.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1250 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921280
protein coding gene Chr2:145675215-145887616 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026594
protein coding gene Chr2:149940921-150050338 (+)
A/J MGP_AJ_G0026558
protein coding gene Chr2:143875680-143985791 (+)
AKR/J MGP_AKRJ_G0026532
protein coding gene Chr2:148044912-148156866 (+)
BALB/cJ MGP_BALBcJ_G0026570
protein coding gene Chr2:144304784-144412532 (+)
C3H/HeJ MGP_C3HHeJ_G0026313
protein coding gene Chr2:148539108-148643698 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027015
protein coding gene Chr2:154388144-154492146 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024392
protein coding gene Chr2:137992066-138107379 (+)
CAST/EiJ MGP_CASTEiJ_G0025774
protein coding gene Chr2:148881816-148995568 (+)
CBA/J MGP_CBAJ_G0026293
protein coding gene Chr2:159982972-160099397 (+)
DBA/2J MGP_DBA2J_G0026427
protein coding gene Chr2:143174340-143278349 (+)
FVB/NJ MGP_FVBNJ_G0026391
protein coding gene Chr2:141712333-141821032 (+)
LP/J MGP_LPJ_G0026531
protein coding gene Chr2:150137730-150245519 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026411
protein coding gene Chr2:164190676-164295268 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027070
protein coding gene Chr2:148045711-148154272 (+)
PWK/PhJ MGP_PWKPhJ_G0025509
protein coding gene Chr2:142845132-142950770 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025310
protein coding gene Chr2:147038995-147142792 (+)
WSB/EiJ MGP_WSBEiJ_G0025847
protein coding gene Chr2:148986299-149092367 (+)



Homology
more
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MACS, RASSF4
  • Links
    NCBI Gene ID: 54453
    neXtProt AC: NX_Q8WYP3
    UniProt: Q8WYP3

  • Chr Location
    20p11.23; chr20:19757610-20002459 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32430
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RIN2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74030 NCBI Gene Model | MGI Sequence Detail 115890 C57BL/6J ±  kb
transcript NM_028724 RefSeq | MGI Sequence Detail 4668 C57BL/6  
polypeptide Q9D684 UniProt | EBI | MGI Sequence Detail 903 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 112
    cDNA 112

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917119, MGI:2139415
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory