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Rin2 Gene Detail
Summary
  • Symbol
    Rin2
  • Name
    Ras and Rab interactor 2
  • Synonyms
    2010003K16Rik, 4632403N06Rik, RASSF4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921280
    NCBI Gene: 74030
Location & Maps
more
  • Sequence Map
    Chr2:145784734-145887616 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      102883 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 71.25 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RIN2, Ras and Rab interactor 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MACS, RASSF4
  • Links
    NCBI Gene ID: 54453
    neXtProt AC: NX_Q8WYP3

  • Chr Location
    20p11.22; chr20:19757610-20002459 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 32430
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: RIN2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human RIN2 associations

Human Disease Mouse Models
       Macs Syndrome   OMIM: 613075
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Rin2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004057 VEGA Gene Model | MGI Sequence Detail 102883 C57BL/6J ±  kb
transcript OTTMUST00000009053 VEGA | MGI Sequence Detail 4641 Not Applicable  
polypeptide OTTMUSP00000004397 VEGA | MGI Sequence Detail 903 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1250 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 112
    cDNA 112

    Microarray probesets 3
Other
Accession IDs
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MGI:1917119, MGI:2139415
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory