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Ndufv2
Gene Detail
Symbol

Name
ID
Ndufv2
NADH dehydrogenase (ubiquinone) flavoprotein 2
MGI:1920150
Synonyms
2900010C23Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
35.26 cM, cytoband E1.2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:66078795-66101559 bp, - strand
From VEGA annotation of GRCm38

  22765 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10884  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 2 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFV2
Protein SuperFamily: NADH dehydrogenase [ubiquinone] (complex I), flavoprotein 2/NADH:quinone oxidoreductase (complex I), NuoE subunit
Gene Tree: Ndufv2

Human
homologs
NDUFV2, NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4729
neXtProt AC: NX_P19404

Human Synonyms: CI-24k

Human Chr (Location): 18p11.22; chr18:9102630-9134345 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFV2

Mutations,
alleles, and
phenotypes
All mutations/alleles(58) : Gene trapped(55) Targeted(2) Transposon induced(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a transposon induced allele may exhibit embryonic lethality at E7.
 
Interactions
Ndufv2 interacts with 247 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (152)    Tissues (104)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 152
cDNA source data(15)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufv2 ; ZFIN ndufv2    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000016284 (Evidence)
Ensembl Gene Model ENSMUSG00000024099 (Evidence)
Entrez Gene 72900 (Evidence)
DFCI TC1574280, TC1596231, TC1606413, TC1641698
DoTS DT.533854, DT.55161834, DT.97351658, DT.99867919, DT.99869457
NIA Mouse Gene Index U038013
EC 1.6.5.3, 1.6.99.3
Consensus CDS Project CCDS37679.1, CCDS70836.1
International Mouse Phenotyping Consortium Status Ndufv2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016284 VEGA Gene Model | MGI Sequence Detail 22765 C57BL/6J ±  kb
transcript OTTMUST00000039096 VEGA | MGI Sequence Detail 1540 Not Applicable 
polypeptide OTTMUSP00000017460 VEGA | MGI Sequence Detail 248 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(18 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002023 NADH-quinone oxidoreductase subunit E-like
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000011105 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:172853 Kohr MJ, et al., Characterization of potential S-nitrosylation sites in the myocardium. Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1327-35
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory