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Ube2cbp Gene Detail
Summary
  • Symbol
    Ube2cbp
  • Name
    ubiquitin-conjugating enzyme E2C binding protein
  • Synonyms
    2610018I03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917598
    NCBI Gene: 70348
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:86307306-86464950 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 46.58 cM, cytoband E3.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1814 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917598
protein coding gene Chr9:86307234-86465172 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035094
protein coding gene Chr9:87130342-87286902 (-)
A/J MGP_AJ_G0035075
protein coding gene Chr9:84078950-84237027 (-)
AKR/J MGP_AKRJ_G0035003
protein coding gene Chr9:86069151-86239983 (-)
BALB/cJ MGP_BALBcJ_G0035063
protein coding gene Chr9:83700376-83877756 (-)
C3H/HeJ MGP_C3HHeJ_G0034775
protein coding gene Chr9:86532995-86699670 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035587
protein coding gene Chr9:89471469-89634343 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032494
protein coding gene Chr9:82864146-83014671 (-)
CAST/EiJ MGP_CASTEiJ_G0034093
protein coding gene Chr9:87006363-87179412 (-)
CBA/J MGP_CBAJ_G0034748
protein coding gene Chr9:92692554-92843041 (-)
DBA/2J MGP_DBA2J_G0034906
protein coding gene Chr9:83636894-83785027 (-)
FVB/NJ MGP_FVBNJ_G0034849
protein coding gene Chr9:82749680-82899605 (-)
LP/J MGP_LPJ_G0034987
protein coding gene Chr9:87344888-87504308 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034891
protein coding gene Chr9:94244347-94421256 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035607
protein coding gene Chr9:86197193-86352144 (-)
PWK/PhJ MGP_PWKPhJ_G0033797
protein coding gene Chr9:83814937-83975026 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033633
protein coding gene Chr9:86394140-86558502 (-)
WSB/EiJ MGP_WSBEiJ_G0034210
protein coding gene Chr9:86227708-86382607 (-)



Homology
more
  • Human Ortholog
    UBE3D, ubiquitin protein ligase E3D
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UBE3D, ubiquitin protein ligase E3D
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf157, H10BH, UBE2CBP, YJR141W
  • Links
    NCBI Gene ID: 90025
    neXtProt AC: NX_Q7Z6J8
    UniProt: Q7Z6J8

  • Chr Location
    6q14.1; chr6:82880834-83065841 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18898
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: UBE3D
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele cannot be obtained. Heterozygotes exhibit abnormal retinal pigment epithelium morphology and decreased a- and b-wave amplitude.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032415 Ensembl Gene Model | MGI Sequence Detail 157645 C57BL/6J ±  kb
transcript ENSMUST00000034986 Ensembl | MGI Sequence Detail 1790 Not Applicable  
polypeptide ENSMUSP00000034986 Ensembl | MGI Sequence Detail 368 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory