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Smco2 Gene Detail
Summary
  • Symbol
    Smco2
  • Name
    single-pass membrane protein with coiled-coil domains 2
  • Synonyms
    1700023A16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916621
    NCBI Gene: 69371
Location & Maps
more
  • Sequence Map
    Chr6:146850104-146871406 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21303 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 77.70 cM, cytoband G3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SMCO2, single-pass membrane protein with coiled-coil domains 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SMCO2, single-pass membrane protein with coiled-coil domains 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C12orf70
  • Links
    NCBI Gene ID: 341346
    neXtProt AC: NX_A6NFE2

  • Chr Location
    12p11.23; chr12:27446744-27502322 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024461 VEGA Gene Model | MGI Sequence Detail 21303 C57BL/6J ±  kb
transcript OTTMUST00000059992 VEGA | MGI Sequence Detail 1276 Not Applicable  
polypeptide OTTMUSP00000029235 VEGA | MGI Sequence Detail 347 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    376 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR026617 Transmembrane and coiled-coil domain-containing protein 2/5
Molecular
Reagents
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  • All nucleic 1
    cDNA 1

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory