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Cwc27 Gene Detail
Summary
  • Symbol
    Cwc27
  • Name
    CWC27 spliceosome-associated protein
  • Synonyms
    3110009E13Rik, NY-CO-10, Sdccag10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914535
    NCBI Gene: 67285
Location & Maps
more
  • Sequence Map
    Chr13:104631140-104817142 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      186003 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 56.64 cM, cytoband D1
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CWC27, CWC27 spliceosome associated protein homolog
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CWC27, CWC27 spliceosome associated protein homolog
    Orthology source: HGNC, HomoloGene
  • Synonyms
    NY-CO-10, SDCCAG10, SDCCAG-10
  • Links
    NCBI Gene ID: 10283
    neXtProt AC: NX_Q6UX04

  • Chr Location
    5q12.3; chr5:64768918-65018763 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 21192
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CWC27
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    26
  • Gene trapped
    19
  • Targeted
    7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029392 VEGA Gene Model | MGI Sequence Detail 186003 C57BL/6J ±  kb
transcript OTTMUST00000072847 VEGA | MGI Sequence Detail 2071 Not Applicable  
polypeptide OTTMUSP00000037595 VEGA | MGI Sequence Detail 469 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    796 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014557 peptidyl-prolyl cis-trans isomerase CWC27
  • EC
  • InterPro Domains
    IPR029000 Cyclophilin-like domain
    IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
    IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Molecular
Reagents
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  • All nucleic 26
    cDNA 26

    Microarray probesets 2
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory