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Mgst3
Gene Detail
Symbol

Name
ID
Mgst3
microsomal glutathione S-transferase 3
MGI:1913697
Synonyms
2010012L10Rik, 2010306B17Rik, 2700004G04Rik, GST-III
Feature Type
protein coding gene
Genetic Map
Chromosome 1
74.76 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr1:167371966-167393841 bp, - strand
From VEGA annotation of GRCm38

  21876 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3327  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MGST3
Gene Tree: Mgst3

Human
homologs
MGST3, microsomal glutathione S-transferase 3
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 4259
neXtProt AC: NX_O14880

Human Synonyms: GST-III

Human Chr (Location): 1q23; chr1:165630873-165656136 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Mgst3 interacts with 60 markers (Mir1b, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, extracellular exosome, ...
Function glutathione peroxidase activity, glutathione transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (223)    Tissues (117)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 223
cDNA source data(164)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase mgst3 ; ZFIN mgst3    NEW 
Molecular
reagents
All nucleic(164) cDNA(164)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000022623 (Evidence)
Ensembl Gene Model ENSMUSG00000026688 (Evidence)
Entrez Gene 66447 (Evidence)
UniGene 218286
DFCI TC1697740, TC1574762
DoTS DT.537065, DT.94406924
NIA Mouse Gene Index U022017, U272867
EC 2.5.1.18
Consensus CDS Project CCDS15457.1
International Mouse Phenotyping Consortium Status Mgst3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022623 VEGA Gene Model | MGI Sequence Detail 21876 C57BL/6J ±  kb
transcript OTTMUST00000054194 VEGA | MGI Sequence Detail 1097 Not Applicable 
polypeptide OTTMUSP00000025829 VEGA | MGI Sequence Detail 153 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(3) UniProt(2)
Polymorphisms
SNPs within 2kb(389 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain
InterPro IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
Protein Ontology PR:000010392 microsomal glutathione S-transferase 3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:219340 Molyneaux BJ, et al., DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21;85(2):275-88
All references(43)
Other
accession IDs
MGI:1915449, MGI:1922953, MGI:2138101

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory