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Cope Gene Detail
Summary
  • Symbol
    Cope
  • Name
    coatomer protein complex, subunit epsilon
  • Synonyms
    1110005D17Rik, Cope1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891702
    NCBI Gene: 59042
Location & Maps
more
  • Sequence Map
    Chr8:70302518-70312993 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10476 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    COPE, coatomer protein complex subunit epsilon
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COPE, coatomer protein complex subunit epsilon
    Orthology source: HGNC, HomoloGene
  • Synonyms
    epsilon-COP
  • Links
    NCBI Gene ID: 11316
    neXtProt AC: NX_O14579

  • Chr Location
    19p13.11; chr19:18899514-18919464 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Targeted
    1
  • Genomic Mutations
    1 involving Cope
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027332 VEGA Gene Model | MGI Sequence Detail 10476 C57BL/6J ±  kb
transcript OTTMUST00000067558 VEGA | MGI Sequence Detail 1300 Not Applicable  
polypeptide OTTMUSP00000034019 VEGA | MGI Sequence Detail 308 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    86 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 219
    cDNA 219

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915825
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:62630 Chu CC, et al., Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Mol Immunol. 1998 Jun;35(8):487-502
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory