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Cope
Gene Detail
Symbol

Name
ID
Cope
coatomer protein complex, subunit epsilon
MGI:1891702
Synonyms
1110005D17Rik, Cope1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
34.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:70302518-70312993 bp, + strand
From VEGA annotation of GRCm38

  10476 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5254  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: COPE
Protein SuperFamily: oatomer, epsilon subunit
Gene Tree: Cope

Human
homologs
COPE, coatomer protein complex, subunit epsilon
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 11316
neXtProt AC: NX_O14579

Human Synonyms: epsilon-COP

Human Chr (Location): 19p13.11; chr19:18899514-18919464 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(6) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cope interacts with 84 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, ...
Component COPI-coated vesicle, COPI vesicle coat, ...
Function structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(219)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cope    NEW 
Molecular
reagents
All nucleic(219) cDNA(219)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000027332 (Evidence)
Ensembl Gene Model ENSMUSG00000055681 (Evidence)
Entrez Gene 59042 (Evidence)
UniGene 28668
DFCI TC1602956, TC1572154, TC1605431
DoTS DT.91432287, DT.87059849, DT.87048916, DT.101207549, DT.55263831
NIA Mouse Gene Index U073816
Consensus CDS Project CCDS22365.1
International Mouse Phenotyping Consortium Status Cope
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027332 VEGA Gene Model | MGI Sequence Detail 10476 C57BL/6J ±  kb
transcript OTTMUST00000067558 VEGA | MGI Sequence Detail 1300 Not Applicable 
polypeptide OTTMUSP00000034019 VEGA | MGI Sequence Detail 308 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(2) UniProt(6)
Polymorphisms
SNPs within 2kb(86 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006822 Coatomer, epsilon subunit
InterPro IPR011990 Tetratricopeptide-like helical
Protein Ontology PR:000005736 coatomer subunit epsilon
References
(Earliest) J:62630 Chu CC, et al., Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Mol Immunol. 1998 Jun;35(8):487-502
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:1915825

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory