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Donson Gene Detail
Summary
  • Symbol
    Donson
  • Name
    downstream neighbor of SON
  • Synonyms
    1110025J21Rik, Donson, ORF60
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890621
    NCBI Gene: 60364
Location & Maps
more
  • Sequence Map
    Chr16:91677268-91688765 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11498 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 53.25 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DONSON, downstream neighbor of SON
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DONSON, downstream neighbor of SON
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B17, C21orf60
  • Links
    NCBI Gene ID: 29980
    neXtProt AC: NX_Q9NYP3

  • Chr Location
    21q22.1; chr21:33577551-33588708 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Targeted
    10
  • Genomic Mutations
    6 involving Donson
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019888 VEGA Gene Model | MGI Sequence Detail 11498 C57BL/6J ±  kb
transcript OTTMUST00000047419 VEGA | MGI Sequence Detail 2360 Not Applicable  
polypeptide OTTMUSP00000021431 VEGA | MGI Sequence Detail 560 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    63 from dbSNP Build 142
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000006638 protein downstream neighbor of Son
  • InterPro Domains
    IPR024861 Donson
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915899, MGI:2146495
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:63039 Sund NJ, et al., Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte. Mol Cell Biol. 2000 Jul;20(14):5175-83
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory