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Mpdu1
Gene Detail
Symbol

Name
ID
Mpdu1
mannose-P-dolichol utilization defect 1
MGI:1346040
Synonyms
LEC35, SL15, Supl15h
Feature Type
protein coding gene
Genetic Map
Chromosome 11
42.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:69656697-69662642 bp, - strand
From VEGA annotation of GRCm38

  5946 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3581  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: MPDU1
Protein SuperFamily: mannose-P-dolichol utilization defect 1 protein
Gene Tree: Mpdu1

Human
homologs
MPDU1, mannose-P-dolichol utilization defect 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9526
neXtProt AC: NX_O75352

Human Synonyms: CDGIF, HBEBP2BPA, Lec35, My008, PP3958, PQLC5, SL15

Human Chr (Location): 17p13.1-p12; chr17:7583647-7588212 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MPDU1

Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Gene trapped(23) Targeted(3)
Genomic Mutations involving Mpdu1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mpdu1 interacts with 94 markers (Mir10b, Mir15a, Mir16-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (12)    Tissues (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
cDNA source data(138)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC548940 ; ZFIN mpdu1a, mpdu1b    NEW 
Molecular
reagents
All nucleic(140) Genomic(1) cDNA(139)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000006008 (Evidence)
Ensembl Gene Model ENSMUSG00000018761 (Evidence)
Entrez Gene 24070 (Evidence)
UniGene 89579
DFCI TC1618675, TC1604444, TC1574270
DoTS DT.87072670, DT.97363466
NIA Mouse Gene Index U032972
Consensus CDS Project CCDS24903.1
International Mouse Phenotyping Consortium Status Mpdu1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006008 VEGA Gene Model | MGI Sequence Detail 5946 C57BL/6J ±  kb
transcript OTTMUST00000013453 VEGA | MGI Sequence Detail 1321 Not Applicable 
polypeptide OTTMUSP00000006229 VEGA | MGI Sequence Detail 247 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(7) UniProt(7)
Polymorphisms
SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006603 Cystinosin/ERS1p repeat
InterPro IPR016817 Mannose-P-dolichol utilization defect 1 protein
Protein Ontology PR:000010531 mannose-P-dolichol utilization defect 1 protein
References
(Earliest) J:57450 Miyashita A, et al., Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. Gene. 1999 Sep 3;237(1):53-60
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory