Mpdu1
Gene Detail

Symbol Name ID

Mpdu1 mannose-P-dolichol utilization defect 1 MGI:1346040

Synonyms

LEC35, SL15, Supl15h

Feature Type

protein coding gene

Genetic Map

Chromosome 11

42.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr11:69656697-69662642 bp, - strand From VEGA annotation of GRCm38   5946 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3581  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: mannose-P-dolichol utilization defect 1 protein
Gene Tree: Mpdu1

Human homologs

Human Homolog		MPDU1, mannose-P-dolichol utilization defect 1
NCBI Gene ID		9526
neXtProt AC		NX_O75352
Human Synonyms		CDGIF, HBEBP2BPA, Lec35, My008, PP3958, PQLC5, SL15
Human Chr (Location)		17p13.1-p12; chr17:7486965-7491530 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human MPDU1

Alleles and phenotypes

All alleles(25) : Targeted(2) Gene trapped(23)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	oligosaccharide biosynthetic process, transport
Component	endoplasmic reticulum, integral to membrane, ...
Function	molecular_function

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (12)    Tissues (6)   
Theiler Stages: 24, 26, 28

Assay Type	Results
RNA in situ	12

cDNA source data(138)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(140) Genomic(1) cDNA(139)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000006008 (Evidence)
Ensembl Gene Model	ENSMUSG00000018761 (Evidence)
Entrez Gene	24070 (Evidence)
UniGene	89579
DFCI	TC1574270, TC1604444
DoTS	DT.87072670, DT.97363466
NIA Mouse Gene Index	U032972
Consensus CDS Project	CCDS24903.1
International Mouse Knockout Project Status	Mpdu1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006008	VEGA Gene Model | MGI Sequence Detail	5946	C57BL/6J
transcript	OTTMUST00000013453	VEGA | MGI Sequence Detail	1321	Not Applicable
polypeptide	OTTMUSP00000006229	VEGA | MGI Sequence Detail	247	Not Applicable

All sequences(58) RefSeq(2) UniProt(7)

Polymorphisms

SNPs(20 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006603	Cystinosin/ERS1p repeat
InterPro	IPR016817	Mannose-P-dolichol utilization defect 1 protein
Protein Ontology	PR:000010531	mannose-P-dolichol utilization defect 1 protein

References

(Earliest) J:57450 Miyashita A, et al., Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. Gene. 1999 Sep 3;237(1):53-60
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)