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Mpdu1 Gene Detail
Summary
  • Symbol
    Mpdu1
  • Name
    mannose-P-dolichol utilization defect 1
  • Synonyms
    LEC35, SL15, Supl15h
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346040
    NCBI Gene: 24070
  • Gene Overview
    MyGene.info: MPDU1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69656697-69662642 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 42.86 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346040
protein coding gene Chr11:69656697-69662649 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018544
protein coding gene Chr11:70113640-70119548 (-)
A/J MGP_AJ_G0018512
protein coding gene Chr11:67472699-67478657 (-)
AKR/J MGP_AKRJ_G0018481
protein coding gene Chr11:69481492-69487435 (-)
BALB/cJ MGP_BALBcJ_G0018484
protein coding gene Chr11:67782434-67788380 (-)
C3H/HeJ MGP_C3HHeJ_G0018297
protein coding gene Chr11:69502055-69507997 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018935
protein coding gene Chr11:72234550-72242407 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016580
protein coding gene Chr11:64391807-64397866 (-)
CAST/EiJ MGP_CASTEiJ_G0017852
protein coding gene Chr11:69753475-69759415 (-)
CBA/J MGP_CBAJ_G0018270
protein coding gene Chr11:75467703-75476489 (-)
DBA/2J MGP_DBA2J_G0018379
protein coding gene Chr11:67054396-67059663 (-)
FVB/NJ MGP_FVBNJ_G0018369
protein coding gene Chr11:66690595-66696465 (-)
LP/J MGP_LPJ_G0018449
protein coding gene Chr11:70679273-70686612 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018392
protein coding gene Chr11:76063638-76069599 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018977
protein coding gene Chr11:69744252-69750979 (-)
PWK/PhJ MGP_PWKPhJ_G0017626
protein coding gene Chr11:67703709-67710084 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017416
protein coding gene Chr11:69558509-69564589 (-)
WSB/EiJ MGP_WSBEiJ_G0017906
protein coding gene Chr11:69415999-69422702 (-)



Homology
more
  • Human Ortholog
    MPDU1, mannose-P-dolichol utilization defect 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MPDU1, mannose-P-dolichol utilization defect 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDGIF, HBEBP2BPA, Lec35, My008, PP3958, PQLC5, SL15, SLC66A5
  • Links
    NCBI Gene ID: 9526
    neXtProt AC: NX_O75352
    UniProt: O75352

  • Chr Location
    17p13.1; chr17:7583647-7588212 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MPDU1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018761 Ensembl Gene Model | MGI Sequence Detail 5946 C57BL/6J ±  kb
transcript ENSMUST00000018905 Ensembl | MGI Sequence Detail 1321 Not Applicable  
polypeptide ENSMUSP00000018905 Ensembl | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR016817 Mannose-P-dolichol utilization defect 1 protein
    IPR006603 PQ-loop repeat
Molecular
Reagents
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  • All nucleic 141
    Genomic 1
    cDNA 140

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory