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Mpdu1
Gene Detail
 Symbol
Name
ID
Mpdu1
mannose-P-dolichol utilization defect 1
MGI:1346040
Synonyms LEC35, SL15, Supl15h
Feature Type protein coding gene
Genetic Map
Chromosome 11
42.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:69656697-69662642 bp, - strand
From VEGA annotation of GRCm38

  5946 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3581  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: mannose-P-dolichol utilization defect 1 protein
Gene Tree: Mpdu1

Human
homologs
Human Homolog MPDU1, mannose-P-dolichol utilization defect 1
NCBI Gene ID 9526
neXtProt AC  NX_O75352
Human Synonyms  CDGIF, HBEBP2BPA, Lec35, My008, PP3958, PQLC5, SL15
Human Chr (Location)  17p13.1-p12; chr17:7583647-7588212 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human MPDU1
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(23) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mpdu1 interacts with 94 markers (Mir10b, Mir15a, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process oligosaccharide biosynthetic process, transport
Component endoplasmic reticulum, extracellular vesicular exosome, ...
Function molecular_function
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (12)    Tissues (7)   
Theiler Stages: 24, 26, 27, 28
Assay TypeResults
RNA in situ 12
cDNA source data(138)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(140) Genomic(1) cDNA(139)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006008 (Evidence)
Ensembl Gene ModelENSMUSG00000018761 (Evidence)
Entrez Gene24070 (Evidence)
UniGene89579
DFCITC1574270, TC1604444, TC1618675
DoTSDT.87072670, DT.97363466
NIA Mouse Gene IndexU032972
Consensus CDS ProjectCCDS24903.1
International Mouse Knockout Project StatusMpdu1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006008 VEGA Gene Model | MGI Sequence Detail 5946 C57BL/6J ±  kb
transcript OTTMUST00000013453 VEGA | MGI Sequence Detail 1321 Not Applicable 
polypeptide OTTMUSP00000006229 VEGA | MGI Sequence Detail 247 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(9) UniProt(7)
Polymorphisms SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006603 Cystinosin/ERS1p repeat
InterPro IPR016817 Mannose-P-dolichol utilization defect 1 protein
Protein Ontology PR:000010531 mannose-P-dolichol utilization defect 1 protein
References (Earliest) J:57450 Miyashita A, et al., Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. Gene. 1999 Sep 3;237(1):53-60
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory