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Ap1g2 Gene Detail
Summary
  • Symbol
    Ap1g2
  • Name
    adaptor protein complex AP-1, gamma 2 subunit
  • Synonyms
    Adtg2, gamma 2-adaptin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328307
    NCBI Gene: 11766
  • Gene Overview
    MyGene.info: AP1G2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55098575-55106593 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 28.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328307
protein coding gene Chr14:55098575-55106975 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021340
protein coding gene Chr14:49099505-49107516 (-)
A/J MGP_AJ_G0021299
protein coding gene Chr14:48119005-48127020 (-)
AKR/J MGP_AKRJ_G0021275
protein coding gene Chr14:49868583-49876597 (-)
BALB/cJ MGP_BALBcJ_G0021303
protein coding gene Chr14:48096623-48104638 (-)
C3H/HeJ MGP_C3HHeJ_G0021083
protein coding gene Chr14:49558705-49566720 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021741
protein coding gene Chr14:51588140-51596155 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019288
protein coding gene Chr14:46524248-46532439 (-)
CAST/EiJ MGP_CASTEiJ_G0020602
protein coding gene Chr14:45807782-45815796 (-)
CBA/J MGP_CBAJ_G0021050
protein coding gene Chr14:53143092-53151104 (-)
DBA/2J MGP_DBA2J_G0021171
protein coding gene Chr14:47858999-47867059 (-)
FVB/NJ MGP_FVBNJ_G0021153
protein coding gene Chr14:47326515-47334525 (-)
LP/J MGP_LPJ_G0021245
protein coding gene Chr14:50150032-50158047 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021177
protein coding gene Chr14:52508406-52516420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021768
protein coding gene Chr14:49054054-49062065 (-)
PWK/PhJ MGP_PWKPhJ_G0020349
protein coding gene Chr14:44399194-44407247 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020177
protein coding gene Chr14:45044901-45052921 (-)
WSB/EiJ MGP_WSBEiJ_G0020655
protein coding gene Chr14:49349789-49357809 (-)



Homology
more
  • Human Ortholog
    AP1G2, adaptor related protein complex 1 subunit gamma 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    AP1G2, adaptor related protein complex 1 subunit gamma 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    G2AD
  • Links
    NCBI Gene ID: 8906
    neXtProt AC: NX_O75843
    UniProt: O75843

  • Chr Location
    14q11.2; chr14:23559563-23569056 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040701 Ensembl Gene Model | MGI Sequence Detail 8019 C57BL/6J ±  kb
transcript ENSMUST00000036041 Ensembl | MGI Sequence Detail 2673 Not Applicable  
polypeptide ENSMUSP00000043996 Ensembl | MGI Sequence Detail 791 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004092 AP-1 complex subunit gamma-like 2
  • InterPro Domains
    IPR017107 Adaptor protein complex AP-1, gamma subunit
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
    IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily
    IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
    IPR008153 Gamma-adaptin ear (GAE) domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:48443 Odorizzi G, et al., The AP-3 complex: a coat of many colours. Trends Cell Biol. 1998 Jul;8(7):282-8
  • Latest
    J:250166 Liu K, et al., Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory