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Ap1g2 Gene Detail
Summary
  • Symbol
    Ap1g2
  • Name
    adaptor protein complex AP-1, gamma 2 subunit
  • Synonyms
    Adtg2, gamma 2-adaptin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328307
    NCBI Gene: 11766
  • Gene Overview
    MyGene.info: AP1G2
Location & Maps
more
  • Sequence Map
    Chr14:55098578-55106593 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8016 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 28.07 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    AP1G2, adaptor related protein complex 1 gamma 2 subunit
  • Vertebrate Orthologs
    7
  • Human Ortholog
    AP1G2, adaptor related protein complex 1 gamma 2 subunit
    Orthology source: HomoloGene
  • Synonyms
    G2AD
  • Links
    NCBI Gene ID: 8906
    neXtProt AC: NX_O75843

  • Chr Location
    14q11.2; chr14:23559563-23569545 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Ap1g2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027952 VEGA Gene Model | MGI Sequence Detail 8016 C57BL/6J ±  kb
transcript OTTMUST00000069237 VEGA | MGI Sequence Detail 2673 Not Applicable  
polypeptide OTTMUSP00000035136 VEGA | MGI Sequence Detail 791 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    74 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004092 AP-1 complex subunit gamma-like 2
  • InterPro Domains
    IPR017107 Adaptor protein complex AP-1, gamma subunit
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
    IPR008153 Clathrin adaptor, gamma-adaptin, appendage
    IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
    IPR013041 Coatomer/clathrin adaptor appendage, Ig-like subdomain
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:48443 Odorizzi G, et al., The AP-3 complex: a coat of many colours. Trends Cell Biol. 1998 Jul;8(7):282-8
  • Latest
    J:190426 Muthusamy N, et al., Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes. J Neurochem. 2012 Oct;123(1):60-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory