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Sall3 Gene Detail
Summary
  • Symbol
    Sall3
  • Name
    spalt like transcription factor 3
  • Synonyms
    B130022O04Rik, Msal, Msal-1, Salt, Spalt
  • Feature Type
    protein coding gene
  • IDs
    MGI:109295
    NCBI Gene: 20689
  • Gene Overview
    MyGene.info: SALL3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80966376-80986578 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 54.11 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109295
protein coding gene Chr18:80966359-80986951 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024599
protein coding gene Chr18:81902984-81924417 (-)
A/J MGP_AJ_G0024566
protein coding gene Chr18:78322303-78342510 (-)
AKR/J MGP_AKRJ_G0024537
protein coding gene Chr18:80660579-80680779 (-)
BALB/cJ MGP_BALBcJ_G0024564
protein coding gene Chr18:78504907-78525391 (-)
C3H/HeJ MGP_C3HHeJ_G0024333
protein coding gene Chr18:80745744-80765972 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025011
protein coding gene Chr18:83985440-84007783 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022442
protein coding gene Chr18:77158362-77178490 (-)
CAST/EiJ MGP_CASTEiJ_G0023806
protein coding gene Chr18:81084294-81105178 (-)
CBA/J MGP_CBAJ_G0024303
protein coding gene Chr18:87050701-87075529 (-)
DBA/2J MGP_DBA2J_G0024433
protein coding gene Chr18:77872304-77892771 (-)
FVB/NJ MGP_FVBNJ_G0024399
protein coding gene Chr18:77184573-77204633 (-)
LP/J MGP_LPJ_G0024517
protein coding gene Chr18:81765109-81786893 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024429
protein coding gene Chr18:88309724-88330288 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025060
protein coding gene Chr18:80813748-80837509 (-)
PWK/PhJ MGP_PWKPhJ_G0023551
protein coding gene Chr18:78273528-78294043 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023357
protein coding gene Chr18:80991038-81012642 (-)
WSB/EiJ MGP_WSBEiJ_G0023868
protein coding gene Chr18:80769144-80791597 (-)



Homology
more
  • Human Ortholog
    SALL3, spalt like transcription factor 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SALL3, spalt like transcription factor 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZNF796
  • Links
    NCBI Gene ID: 27164
    neXtProt AC: NX_Q9BXA9
    UniProt: Q9BXA9

  • Chr Location
    18q23; chr18:78980275-78998969 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18142
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SALL3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice display neonatal lethality with an impaired suckling ability, truncated soft palate, small epiglottis, and abnormal cranial nerve morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024565 Ensembl Gene Model | MGI Sequence Detail 20203 C57BL/6J ±  kb
    transcript ENSMUST00000057950 Ensembl | MGI Sequence Detail 6886 Not Applicable  
    polypeptide ENSMUSP00000056967 Ensembl | MGI Sequence Detail 1248 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 46
      Genomic 1
      cDNA 42
      Primer pair 2
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-36133, MGD-MRK-38340, MGI:2442452
    References
    more
    • Summaries
      All 59
      Developmental Gene Expression 29
      Gene Ontology 6
      Phenotypes 7
    • Earliest
      J:33754 Ott T, et al., The mouse homolog of the region specific homeotic gene spalt of Drosophila is expressed in the developing nervous system and in mesoderm-derived structures. Mech Dev. 1996 May;56(1-2):117-28
    • Latest
      J:261809 Mayer C, et al., Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory