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Sall3 Gene Detail
Summary
  • Symbol
    Sall3
  • Name
    spalt like transcription factor 3
  • Synonyms
    B130022O04Rik, Msal, Msal-1, Salt, Spalt
  • Feature Type
    protein coding gene
  • IDs
    MGI:109295
    NCBI Gene: 20689
  • Gene Overview
    MyGene.info: SALL3
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr18:80966376-80986578 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20203 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 54.11 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SALL3, spalt like transcription factor 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SALL3, spalt like transcription factor 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZNF796
  • Links
    NCBI Gene ID: 27164
    neXtProt AC: NX_Q9BXA9
    UniProt: Q9BXA9

  • Chr Location
    18q23; chr18:78980275-78998969 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18142
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SALL3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice display neonatal lethality with an impaired suckling ability, truncated soft palate, small epiglottis, and abnormal cranial nerve morphology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024565 Ensembl Gene Model | MGI Sequence Detail 20203 C57BL/6J ±  kb
    transcript ENSMUST00000057950 Ensembl | MGI Sequence Detail 6886 Not Applicable  
    polypeptide ENSMUSP00000056967 Ensembl | MGI Sequence Detail 1248 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      71 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 45
      Genomic 1
      cDNA 41
      Primer pair 2
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-36133, MGD-MRK-38340, MGI:2442452
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 29
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:33754 Ott T, et al., The mouse homolog of the region specific homeotic gene spalt of Drosophila is expressed in the developing nervous system and in mesoderm-derived structures. Mech Dev. 1996 May;56(1-2):117-28
    • Latest
      J:261809 Mayer C, et al., Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory