Both an ENU-induced mutation and a null mutation are midgestation lethal. Observed defects include failure of neural tube closure and heart and gut defects. Conditional knockouts in chondrocytes and dental epithelium result in short long bones and dentalepithelium derivative defects, respectively.
|Process||anterior/posterior pattern specification, astrocyte activation, ...|
|Component||axonal growth cone, caveola, ...|
|Function||drug binding, G-protein coupled receptor activity, ...|
|VEGA Gene Model||OTTMUSG00000013446 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000001761 (Evidence)|
|Entrez Gene||319757 (Evidence)|
|DoTS||DT.55267335, DT.101736449, DT.101394450, DT.87072474, DT.94249037|
|NIA Mouse Gene Index||U089023, U006619|
|Consensus CDS Project||CCDS19965.1|
|International Mouse Knockout Project Status||Smo|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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