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hb Gene Detail
Summary
  • Symbol
    hb
  • Name
    head bobber
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:107756
    NCBI Gene: 15120
  • Alliance
Location &
Maps
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  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice exhibit head bobbing, hyperactivity and circling behavior. They are also deaf. Semicircular canals are absent from the inner ear and Reissner's membrane is collapsed.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-36332
References
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  • Summaries
    All 7
    Phenotypes 4
  • Earliest
    J:30311 Steel KP, Inherited hearing defects in mice. Annu Rev Genet. 1995;29:675-701
  • Latest
    J:197180 Buniello A, et al., Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory