About   Help   FAQ
Ppih
Gene Detail
Symbol

Name
ID
Ppih
peptidyl prolyl isomerase H
MGI:106499
Synonyms
1100001J08Rik, 2010111B15Rik, 4833408F11Rik, cyclophilin H, CYP-20, D4Wsu43e, rotamase H
Feature Type
protein coding gene
Genetic Map
Chromosome 4
55.34 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr4:119300010-119320546 bp, - strand
From VEGA annotation of GRCm38

  20537 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38172  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Peptidylpro_ismrse
Gene Tree: Ppih

Human
homologs
Human Homolog PPIH, peptidylprolyl isomerase H (cyclophilin H)
NCBI Gene ID 10465
neXtProt AC  NX_O43447
Human Synonyms  CYP-20, CYPH, SnuCyp-20, USA-CYP
Human Chr (Location)  1p34.1; chr1:42658358-42676758 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(9) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ppih interacts with 125 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process mRNA processing, positive regulation of viral genome replication, ...
Component cytoplasm, nuclear speck, ...
Function isomerase activity, peptidyl-prolyl cis-trans isomerase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (34)    Tissues (30)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 28
RT-PCR 6
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000009258 (Evidence)
Ensembl Gene ModelENSMUSG00000060288 (Evidence)
Entrez Gene66101 (Evidence)
DFCITC1591066, TC1590365, TC1585818, TC1578382, TC1745312
DoTSDT.101182006, DT.101407868, DT.55100528, DT.40144106, DT.110689265, DT.55279059, DT.97369684
EC5.2.1.8
Consensus CDS ProjectCCDS18580.1, CCDS51288.1
International Mouse Knockout Project StatusPpih
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009258 VEGA Gene Model | MGI Sequence Detail 20537 C57BL/6J ±  kb
transcript OTTMUST00000020969 VEGA | MGI Sequence Detail 613 Not Applicable 
polypeptide OTTMUSP00000009611 VEGA | MGI Sequence Detail 188 Not Applicable 

For the selected sequences
All sequences(75) RefSeq(6) UniProt(11)
Polymorphisms
SNPs within 2kb(78 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002130 Cyclophilin-like peptidyl-prolyl cis-trans isomerase domain
InterPro IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
InterPro IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Protein Ontology PR:000013082 peptidyl-prolyl cis-trans isomerase H
References
(Earliest) J:48983 Zhao Y, et al., Mus spretus LINE-1s in C57BL/6J map to at least two different chromosomes. Mamm Genome. 1998 Aug;9(8):679-80
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)
Other
accession IDs
MGD-MRK-34193, MGI:1913351, MGI:1919313, MGI:1921150, MGI:2140301

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory