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Ppih Gene Detail
Summary
  • Symbol
    Ppih
  • Name
    peptidyl prolyl isomerase H
  • Synonyms
    1100001J08Rik, 2010111B15Rik, 4833408F11Rik, cyclophilin H, CYP-20, D4Wsu43e, rotamase H
  • Feature Type
    protein coding gene
  • IDs
    MGI:106499
    NCBI Gene: 66101
  • Gene Overview
    MyGene.info: PPIH
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:119300010-119320523 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 55.34 cM, cytoband D
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106499
protein coding gene Chr4:119300010-119320546 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028696
protein coding gene Chr4:120488844-120510568 (-)
A/J MGP_AJ_G0028656
protein coding gene Chr4:115755545-115776063 (-)
AKR/J MGP_AKRJ_G0028609
protein coding gene Chr4:118264542-118284778 (-)
BALB/cJ MGP_BALBcJ_G0028679
protein coding gene Chr4:116372345-116400059 (-)
C3H/HeJ MGP_C3HHeJ_G0028394
protein coding gene Chr4:119833390-119853952 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029120
protein coding gene Chr4:125061903-125085047 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026397
protein coding gene Chr4:109856492-109877748 (-)
CAST/EiJ MGP_CASTEiJ_G0027825
protein coding gene Chr4:117157975-117180337 (-)
CBA/J MGP_CBAJ_G0028361
protein coding gene Chr4:128444727-128470936 (-)
DBA/2J MGP_DBA2J_G0028508
protein coding gene Chr4:116346309-116367388 (-)
FVB/NJ MGP_FVBNJ_G0028474
protein coding gene Chr4:114865996-114886646 (-)
LP/J MGP_LPJ_G0028608
protein coding gene Chr4:120605304-120627825 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028502
protein coding gene Chr4:133309190-133331788 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029157
protein coding gene Chr4:119342017-119362534 (-)
PWK/PhJ MGP_PWKPhJ_G0027548
protein coding gene Chr4:113269291-113290292 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027374
protein coding gene Chr4:115761965-115782718 (-)
WSB/EiJ MGP_WSBEiJ_G0027905
protein coding gene Chr4:119345356-119367043 (-)



Homology
more
  • Human Ortholog
    PPIH, peptidylprolyl isomerase H
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPIH, peptidylprolyl isomerase H
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CYP-20, CYPH, SnuCyp-20, USA-CYP
  • Links
    NCBI Gene ID: 10465
    neXtProt AC: NX_O43447
    UniProt: O43447

  • Chr Location
    1p34.2; chr1:42657770-42681654 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66101 NCBI Gene Model | MGI Sequence Detail 20514 C57BL/6J ±  kb
transcript NM_001110129 RefSeq | MGI Sequence Detail 2197 C57BL/6  
polypeptide NP_001103600 RefSeq | MGI Sequence Detail 188 C57BL/6  
For the selected sequence
Molecular
Reagents
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  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 10
Other
Accession IDs
less
MGD-MRK-34193, MGI:1913351, MGI:1919313, MGI:1921150, MGI:2140301
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:48983 Zhao Y, et al., Mus spretus LINE-1s in C57BL/6J map to at least two different chromosomes. Mamm Genome. 1998 Aug;9(8):679-80
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory