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Sle3 QTL Detail
Summary
  • Symbol
    Sle3
  • Name
    systemic lupus erythmatosus susceptibility 3
  • Feature Type
    QTL
  • IDs
    MGI:105955
    NCBI Gene: 112365
Location &
Maps
more
  • Sequence Map
    Chr7:3511728-87142720 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    3 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-33634
References
more
  • Summaries
    All 42
    Phenotypes 25
  • Earliest
    J:25006 Morel L, et al., Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity. 1994 Jun;1(3):219-29
  • Latest
    J:335845 Gong M, et al., Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice. iScience. 2023 May 19;26(5):106774
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory