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t Gene Detail
Summary
  • Symbol
    t
  • Name
    t-complex
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:105076
    NCBI Gene: 20998
  • Alliance
Location &
Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 17, Syntenic
  • Mapping Data
    23 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    49 phenotypes from 43 alleles in 10 genetic backgrounds
    48 phenotypes from multigenic genotypes
    115 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice carrying a t haplotype and heterozygous for a dominant brachyury allele are tailless. Mice inheriting specific combinations of t haplotypes may show transmission ratio distortion, recombination suppression, male sterility, or lethality.
Expression
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  • Other Mouse Links
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-1684, MGD-MRK-32116, MGI:1203518, MGI:88217
References
more
  • Summaries
    All 138
    Phenotypes 115
  • Earliest
    J:176338 Chesley P, et al., The Inheritance of Taillessness (Anury) in the House Mouse. Genetics. 1936 Sep;21(5):525-36
  • Latest
    J:273736 Charron Y, et al., Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype. PLoS Genet. 2019 Feb;15(2):e1007964

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory