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In(4)56Rk Cytogenetic Marker Detail
Summary
  • Symbol
    In(4)56Rk
  • Name
    inversion, Chr 4, Roderick 56
  • Synonyms
    Gnb1Rd4, In56Rk
  • Feature Type
    chromosomal inversion
  • IDs
    MGI:103782
    NCBI Gene: 16287
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 4, Syntenic
  • Mapping Data
    6 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a spontaneous mutation found in a stock carrying the large Chr 4 inversion In(4)56Rk exhibit prenatal lethality; heterozygotes display abnormal eye electrophysiology, attenuated retinal vessels, pigment spots, ocular fundus atrophy, and retinal degeneration.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-13814, MGD-MRK-25103, MGI:97885
References
more
  • Summaries
    All 10
    Phenotypes 7
  • Earliest
    J:41514 Roderick TH, et al., A new dominant retinal degeneration (Rd4) associated with a chromosomal inversion in the mouse. Genomics. 1997 Jun 15;42(3):393-6
  • Latest
    J:220643 Tochitsky I, et al., Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells. Neuron. 2014 Feb 19;81(4):800-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory