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Srprb Gene Detail
Summary
  • Symbol
    Srprb
  • Name
    signal recognition particle receptor, B subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:102964
    NCBI Gene: 20818
  • Gene Overview
    MyGene.info: SRPRB
Location & Maps
more
  • Sequence Map
    Chr9:103188032-103202137 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14106 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 55.00 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SRPRB, SRP receptor beta subunit
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SRPRB, SRP receptor beta subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APMCF1
  • Links
    NCBI Gene ID: 58477
    neXtProt AC: NX_Q9Y5M8

  • Chr Location
    3q22.1; chr3:133784033-133821492 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035366 VEGA Gene Model | MGI Sequence Detail 14106 C57BL/6J ±  kb
transcript OTTMUST00000090347 VEGA | MGI Sequence Detail 3064 Not Applicable  
polypeptide OTTMUSP00000049544 VEGA | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015633 signal recognition particle receptor subunit beta
  • PDB
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR019009 Signal recognition particle receptor, beta subunit
    IPR024156 Small GTPase superfamily, ARF type
Molecular
Reagents
less
  • All nucleic 141
    cDNA 141

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-23801, MGI:2142932
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:22490 Miller JD, et al., The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. J Cell Biol. 1995 Feb;128(3):273-82
  • Latest
    J:197701 Lang S, et al., Different effects of Sec61alpha, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci. 2012 Apr 15;125(Pt 8):1958-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory