About   Help   FAQ
Ccng1
Gene Detail
Symbol

Name
ID
Ccng1
cyclin G1
MGI:102890
Synonyms
cyclin G
Feature Type
protein coding gene
Genetic Map
Chromosome 11
24.42 cM, cytoband B1.1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:40748552-40755311 bp, - strand
From VEGA annotation of GRCm38

  6760 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2995  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CCNG1
Gene Tree: Ccng1

Human
homologs
CCNG1, cyclin G1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 900
neXtProt AC: NX_P51959

Human Synonyms: CCNG

Human Chr (Location): 5q32-q34; chr5:163437270-163445016 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Depending on the allele, homozygous mutants exhibit increased cellular sensitivity to gamma-irradiation or decreased incidence of induced hepatic tumors.
 
Interactions
Ccng1 interacts with 325 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, cell division, ...
Component dendrite, neuronal cell body, ...
Function protein domain specific binding
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (70)    Tissues (55)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 6
Northern blot 15
Western blot 2
RT-PCR 47
cDNA source data(23)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ccng1 ; ZFIN ccng1    NEW 
Molecular
reagents
All nucleic(29) Genomic(4) cDNA(23) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000005434 (Evidence)
Ensembl Gene Model ENSMUSG00000020326 (Evidence)
Entrez Gene 12450 (Evidence)
DFCI TC1759392, TC1573987
DoTS DT.535671, DT.97335373, DT.55135202
NIA Mouse Gene Index U296092, U032668
Consensus CDS Project CCDS24550.1
International Mouse Phenotyping Consortium Status Ccng1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005434 VEGA Gene Model | MGI Sequence Detail 6760 C57BL/6J ±  kb
transcript OTTMUST00000012107 VEGA | MGI Sequence Detail 3512 Not Applicable 
polypeptide OTTMUSP00000005602 VEGA | MGI Sequence Detail 294 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(4) UniProt(7)
Polymorphisms
SNPs within 2kb(12 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000005128 cyclin-G1
References
(Earliest) J:21236 Okamoto K, et al., Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO J. 1994 Oct 17;13(20):4816-22
(Latest) J:204566 Gendrel AV, et al., Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
All references(51)
Other
accession IDs
MGD-MRK-23724, MGI:2144106

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory