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Ccng1 Gene Detail
Summary
  • Symbol
    Ccng1
  • Name
    cyclin G1
  • Synonyms
    cyclin G
  • Feature Type
    protein coding gene
  • IDs
    MGI:102890
    NCBI Gene: 12450
  • Gene Overview
    MyGene.info: CCNG1
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:40748552-40755311 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 24.42 cM, cytoband B1.1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102890
protein coding gene Chr11:40748552-40755315 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018163
protein coding gene Chr11:39415047-39421806 (-)
A/J MGP_AJ_G0018136
protein coding gene Chr11:37922355-37929114 (-)
AKR/J MGP_AKRJ_G0018100
protein coding gene Chr11:39035151-39041910 (-)
BALB/cJ MGP_BALBcJ_G0018105
protein coding gene Chr11:38116906-38123665 (-)
C3H/HeJ MGP_C3HHeJ_G0017918
protein coding gene Chr11:39062136-39068895 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018559
protein coding gene Chr11:40599834-40606593 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016214
protein coding gene Chr11:36149262-36156024 (-)
CAST/EiJ MGP_CASTEiJ_G0017482
protein coding gene Chr11:39090896-39097702 (-)
CBA/J MGP_CBAJ_G0017891
protein coding gene Chr11:42509327-42516086 (-)
DBA/2J MGP_DBA2J_G0018001
protein coding gene Chr11:37673393-37680152 (-)
FVB/NJ MGP_FVBNJ_G0017995
protein coding gene Chr11:37424846-37431605 (-)
LP/J MGP_LPJ_G0018073
protein coding gene Chr11:39653824-39660583 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018019
protein coding gene Chr11:43803324-43809922 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018598
protein coding gene Chr11:39101298-39108057 (-)
PWK/PhJ MGP_PWKPhJ_G0017263
protein coding gene Chr11:37748807-37755626 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017055
protein coding gene Chr11:38934524-38941278 (-)
WSB/EiJ MGP_WSBEiJ_G0017531
protein coding gene Chr11:38823611-38830370 (-)



Homology
more
  • Human Ortholog
    CCNG1, cyclin G1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCNG1, cyclin G1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCNG
  • Links
    NCBI Gene ID: 900
    neXtProt AC: NX_P51959
    UniProt: P51959

  • Chr Location
    5q34; chr5:163437567-163445016 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2995
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCNG1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Depending on the allele, homozygous mutants exhibit increased cellular sensitivity to gamma-irradiation or decreased incidence of induced hepatic tumors.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020326 Ensembl Gene Model | MGI Sequence Detail 6760 C57BL/6J ±  kb
    transcript ENSMUST00000020576 Ensembl | MGI Sequence Detail 3512 Not Applicable  
    polypeptide ENSMUSP00000020576 Ensembl | MGI Sequence Detail 294 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 33
      Genomic 4
      cDNA 24
      Primer pair 4
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-23724, MGI:2144106
    References
    more
    • Summaries
      All 64
      Developmental Gene Expression 21
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:254597 Bhargava S, et al., The epigenetic modifier Fam208a is required to maintain epiblast cell fitness. Sci Rep. 2017 Aug 24;7(1):9322

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory