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Cd1 Complex/Cluster/Region Detail
Summary
  • Symbol
    Cd1
  • Name
    CD1 antigen complex
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:102561
    NCBI Gene: 111334
  • Cluster Members
    Cd1d2, Cd1d1 (2 members)
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 3, Syntenic
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • PCR
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 2 genetic backgrounds
    116 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Animals homozygous for a mutation in this gene lack an NK-like cell subset (HSA<-/low>, NK1.1+, TCRint, CD44high, CD122+) of thymocytes. TCR cross-linking and anti-CD3 stimulation fails to induce IL-4 production.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 1
    Primer pair 1
Other
Accession IDs
less
MGD-MRK-19430
References
more
  • Summaries
    All 137
    Phenotypes 116
  • Earliest
    J:10078 Roopenian DC, et al., Responses against antigens encoded by the H-3 histocompatibility locus: antigens stimulating class I MHC- and class II MHC-restricted T cells are encoded by separate genes. Immunogenetics. 1989;30(5):335-43
  • Latest
    J:295350 Johansen MD, et al., Animal and translational models of SARS-CoV-2 infection and COVID-19. Mucosal Immunol. 2020 Aug 20;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory