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Symbol
Name
ID
Chromosome
Adam17
a disintegrin and metallopeptidase domain 17
MGI:1096335
12
9 mapping experiments
Experiment Type Details Chromosome Reference
CROSS Cross Type: Backcross
Mapping Panel: Copeland-Jenkins
12 J:57143 Cerretti DP, et al., Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25. Cytokine. 1999 Aug;11(8):541-51
CROSS Cross Type: Backcross
12 J:160781 Hassemer EL, et al., The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17. Genetics. 2010 May;185(1):245-55
CROSS Cross Type: Backcross
Mapping Panel: JAX (BSS)
12 J:59904 Wagener R, et al., Structure and mapping of the mouse matrilin-3 gene (Matn3), a member of a gene family containing a U12-type AT-AC intron. Mamm Genome. 2000 Feb;11(2):85-90
CROSS Cross Type: Backcross
Mapping Panel: JAX (BSS)
12 J:47651 Yamazaki K, et al., Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12. Genomics. 1998 Apr 15;49(2):336-7
TEXT-QTL 12 J:56090 Mu JL, et al., Quantitative trait loci analysis for the differences in susceptibility to atherosclerosis and diabetes between inbred mouse strains C57BL/6J and C57BLKS/J. J Lipid Res. 1999 Jul;40(7):1328-35
TEXT-QTL 12 J:104621 Teupser D, et al., Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor-/- mice. Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):123-8
TEXT-QTL-Candidate Genes 19 J:149028 Holdt LM, et al., Increased ADAM17 mRNA expression and activity is associated with atherosclerosis resistance in LDL-receptor deficient mice. Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1097-103
TEXT-QTL-Candidate Genes 12 J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33
TEXT-Radiation Hybrid 12 J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory