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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    1
  • Reference
    J:187953 Zhang Z, et al., Genetic analysis of atherosclerosis and glucose homeostasis in an intercross between C57BL/6 and BALB/cJ apolipoprotein E-deficient mice. Circ Cardiovasc Genet. 2012 Apr 1;5(2):190-201
  • ID
    MGI:5661869
Genes
GeneAlleleAssay TypeDescription
Bglu12 visible phenotype
D1Mit495
Notes
  • Experiment
    Linkage analysis was performed on 266 female (B6.129P2-Apoetm1Unc/J x C.129P2(B6)-Apoetm1Unc)F2 intercross mice using 130 SNP markers to identify QTL associated with fasting plasma blood glucose level on a Chow diet.

    QTL Bglu12 maps to 48.3 - 78.3 cM on Chromosome 1 with a peak LOD score of 3.94 at D1Mit495 (60.3 cM) in linkage with plasma blood glucose level. C.129P2(B6)-Apoetm1Unc alleles confer increased susceptibility to higher plasma blood glucose levels on Chow diet with an additive mode ofinheritance.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory