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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    18
  • Reference
    J:36996 van Wezel T, et al., Gene interaction and single gene effects in colon tumour susceptibility in mice [see comments]. Nat Genet. 1996 Dec;14(4):468-70
  • ID
    MGI:47963
Genes
GeneAlleleAssay TypeDescription
Scc5 resistance/susceptibility
D18Mit57 PCR amplified length variant
Notes
  • Experiment
    QTL analysis of 192 (BALB/c x Ccs-19)F2 mice revealed a new colon tumor susceptibility locus, Scc5, tightly linked to D18Mit57 on mouse Chromosome 18 (P = 0.25). Authors note that Scc4 and Scc5 have no apparent individual effect, but that they show a strong reciprocal interaction (P = 0.0064).

    Authors suggest Tgfb2, Msh2, Apc and Grl1 as possible candidate genes for Scc2, Scc3, Scc4 and Scc5 respectively.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory