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Mapping Data
Experiment
  • Experiment
    TEXT
  • Chromosome
    3
  • Reference
    J:33172 Yui MA, et al., Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits. Mamm Genome. 1996 May;7(5):331-4
  • ID
    MGI:46667
Genes
GeneAlleleAssay TypeDescription
Idd3 resistance/susceptibility
Idd10 resistance/susceptibility
D3Mit132 PCR amplified length variant
Il2 reported elsewhere
D3Nds1 reported elsewhere
Tshb reported elsewhere
Notes
  • Experiment
    Microsatellite sequences were used as co-dominant markers to identify/map NOD mouse intervals containing recessive susceptibility alleles of insulin-related diabetes-associated genes. These intervals were transferred to C57BL/6, a resistant strain background, to produce 6 congenic strains. A gain of phenotype strategy was used in their construction. B6.NODc3 mice contain intervals Idd3 (Il2) and Idd10 (Tshb); the order of associated markers was reported as D3Mit132 - Il2 - D3Nds1 - Tshb over a distance of 43 cM on mouse Chromosome 3.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory