About   Help   FAQ
Mapping Data
Experiment
  • Experiment
    TEXT-Physical Mapping
  • Chromosome
    6
  • Reference
    J:32009 Innis JW, et al., Orientation of the Hoxa complex and placement of the Hd locus distal to Hoxa2 on mouse chromosome 6. Mamm Genome. 1996 Mar;7(3):216-7
  • ID
    MGI:46376
Genes
GeneAlleleAssay TypeDescription
Hoxa1 overlapping clones P1-306, P1-4.1.1
D6Mit93 PCR amplified length variant D975
Hoxa2 overlapping clones P1-306, P1-4.1.1
Hoxa3 overlapping clones P1-306, P1-4.1.1
Hoxa4 overlapping clones P1-306, P1-4.1.1
Hoxa5 overlapping clones P1-306, P1-4.1.1
Hoxa6 overlapping clones P1-306, P1-4.1.1
Hoxa7 overlapping clones P1-306, P1-4.1.1, P1-1.10
Hoxa9 overlapping clones P1-306, P1-4.1.1
Hoxa10 overlapping clones P1-306, P1-4.1.1
Hoxa11 overlapping clones P1-306, P1-4.1.1
Hoxa13 Hoxa13Hd visible phenotype
Evx1 PCR amplified length variant
Notes
  • Experiment
    The authors physically mapped the following genes on mouse Chromosome 6 using overlapping phage clones P1-Evx, P1-1.10, P1-306 and P1-4.1.1: Hoxa1, Hoxa2, Hoxa3, Hoxa4, Hoxa5, Hoxa6, Hoxa7, Hoxa9, Hoxa10, Hoxa11, Hoxa13 and Evx1. A recombinational breakpoint was determined to exist in two of the (B6C3Fe-a/a-Hd x M. spretus)F1 x B6C3Fe +/+ mice in the region between D6Mit93 (Hoxa2) and (Hoxa9). RFLP analysis of Hd using D6Mit93 PCR products was consistent with the marker being close to this mutation. The most 5' gene of the Hox cluster (Hoxa13) was suggested to possibly be the best candidate for initial screening for Hd because of reported phenotypes of Hoxa10 and Hoxa11 mice, and the more distal effects observed in Hd mice.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/13/2021
MGI 6.16
The Jackson Laboratory