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Mapping Data
  • Experiment
  • Chromosome
  • Reference
    J:27407 Pathak BG, et al., Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl). Genomics. 1995 Jul 1;28(1):116-8
  • ID
GeneAlleleAssay TypeDescription
Ttr reported elsewhere
Apc reported elsewhere
Hbegf Southern analysis Hegfl cDNA1
Fgf1 reported elsewhere
  • Reference
    Because the sequence and RFLV sizes are nearly identical and because Sdgf and Areg cosegregated in 183 mice, the authors suggest that Sdgf and Areg are species variants derived from the same gene.
  • Experiment
    Offspring types indicate alleles inherited from F1 parent.
  • Type
    Backcross, female
  • Female Parent
    <b> <b> <b> <b>/<s> <s> <s> <s>
  • Strain
    (C57BL/6J x M. spretus)F1
  • Male Parent
    <b> <b> <b> <b>/<b> <b> <b> <b>
  • Strain
  • Mapping Panel
  • Allele 1
    b from C57BL/6J
  • Allele 2
    s from M. spretus
MC #mice Ttr Apc Hbegf Fgf1
72 b b b b
49 s s s s
5 s b b b
5 b s s s
0 s s b b
0 b b s s
4 s s s b
3 b b b s
Additional Mice Typed Only for Specific Pairs of Loci
Marker 1 Marker 2 # Recombinants # Parentals
Ttr Apc 4 22
Apc Hbegf 0 26
Hbegf Fgf1 1 23
Marker 1 Marker 2 # Recombinants Total % Recombinants Std Error
Ttr Apc 14 164 8.537 2.182
Apc Hbegf 0 164 0.000 0.000
Hbegf Fgf1 8 162 4.938 1.702

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory