About   Help   FAQ
Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    2
  • Reference
    J:153429 Umemori J, et al., QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains. BMC Genet. 2009;10:40
  • ID
    MGI:4418225
Genes
GeneAlleleAssay TypeDescription
Hylaq1
D2Mit126
D2Mit423
Hylaq2
D2Mit22
D2Mit29
Notes
  • Experiment
    KJR/Ms (wild strain Korea) mice exhibit a higher home cage activity then do C57BL/6J mice. A genome wide scan using 135 microsatellite markers and 274 (C57BL/6J X KJR/Ms)F2 mice was used to identify genomic regions contributing to the difference in homecage activity. QTL analysis revealed that three loci had an effect on home cage activity. It should be noted that there were three measures of cage activity, AT or active time, AA or average activity and THA or total spontaneous home cage activity which all appear to covariate in the genome scan. A composite QTL was presented as Hyla (hyperlocomotor activity) to symbolize these activities. Hylaq1 mapped to mouse Chromosome 2 with a peak between D2Mit126 and D2Mit423. Hylaq2 also mapped to mouse Chromosome 2 with a peak between D2Mit22 and D2Mit29. Hylaq3 mapped to mouse Chromosome 10 with a peak between D10Mit73 and D10Mit180.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
11/22/2022
MGI 6.22
The Jackson Laboratory