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Mapping Data
Experiment
  • Experiment
    TEXT
  • Chromosome
    4
  • Reference
    J:18898 Rinchik EM, et al., Molecular genetics of the brown (b)-locus region of mouse chromosome 4. I. Origin and molecular mapping of radiation- and chemical-induced lethal brown deletions. Genetics. 1994 Jul;137(3):845-54
  • ID
    MGI:43956
Genes
GeneAlleleAssay TypeDescription
Whrn Whrnwi visible phenotype
D4Rck4 Southern analysis D4Rck4 genomic
D4Rck52 Southern analysis D4Rck52 genomic
Tyrp1 Tyrp1b Southern analysis MT4.Pv.25
D4Rck140 Southern analysis D4Rck140 genomic
Plin2 Southern analysis Adfp genomic1
Ifna PCR amplified length variant F1
Notes
  • Experiment
    Analysis of 25 lethal b mutations permitted the authors to map loci surronding the b locus. The b11R30M deletion encompassed wi, D4Rck4 and D4Rck52 but not D4Rck140. It was determined that D4Rck140 is distal to b and D4Rck4 and D4Rck52 are proximal to b because D4Rck140 was absent in several b deletions that did not include D4Rck4 and D4Rck52. The deletion of D4Rck52 but not D4Rck4 in both b34PSh and b11PU demonstrates that D4Rck52 maps between D4Rck4 and b. The order of loci in the b region is Whrn,D4Rck4, D4Rck52, Tyrp1, D4Rck140, Adfp and Ifa.

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory