Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  2
• Reference
  J:18309 Hess EJ, et al., Deletion map of the coloboma (Cm) locus on mouse chromosome 2. Genomics. 1994 May 1;21(1):257-61
• ID
  MGI:43711

Genes

Gene	Assay Type	Description
Plcb1	Southern analysis	Plcb cDNA1
Cm	visible phenotype
Pcsk2	Southern analysis	mPC2

Notes

• Reference
  The authors use Bmp-2a, Plcb-1 and Nec-2 for Bmp2, Plcb and Pcsk2 respectively. This study identifies two genes, Plcb and Snap, that may be considered candidate genes for Cm.
• Experiment
  Southern blot analysis on C3H/HeJ and Cm/+ crossed with M. spretus interspecific hybrids placed Plcb within the region of the Cm deletion but placed Pcsk2 outside the Cm deletion.