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Mapping Data
  • Experiment
    TEXT-Genetic Cross
  • Chromosome
  • Reference
    J:19442 Nagle DL, et al., Structural analysis of chromosomal rearrangements associated with the developmental mutations Ph, W19H, and Rw on mouse chromosome 5. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7237-41
  • ID
GeneAlleleAssay TypeDescription
D5Buc1 Southern analysis D5Buc1 probe1
D5Mnl25e Southern analysis D5Mnl25 cDNA1
D5Buc2 PFGE D5Buc2 genomic1
Pdgfra Southern analysis Pdgfra probe2
D5Buc3 Southern analysis D5Buc3 genomic1
Kit Southern analysis Kit probe2
Kdr Southern analysis Flk1 probe2
Ph visible phenotype
  • Experiment
    Deletion mapping of the F1 progeny from two interspecific crosses, C57BL/6J-Ph x M. spretus and C57BL/6J-W19h x M. spretus, revealed that D5Buc1 maps outside the W19h and Ph deletions; D5Mnl25, Kit and Flk1 are deleted in the W19h but not the Ph chromosome while Pdgfra is deleted on both the W19h and Ph chromosomes. One other locus, D5Buc3, maps within the Ph deletion but D5Buc2 maps outside the deletion. Pulse Field Gel Electrophoresis (PFGE) confirmed that D5Buc2 maps 50kb proximal to the Ph deletion breakpoint.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.20
The Jackson Laboratory