Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:151159 Bennett B, et al., Genetic dissection of quantitative trait locus for ethanol sensitivity in long- and short-sleep mice. Genes Brain Behav. 2008 Aug;7(6):659-68
• ID
  MGI:4367113

Genes

Gene
Lore1
D1Mit180
D1Mit192

Notes

• Experiment
  A multistage mapping strategy involving Long sleep (LS) and short-sleep (SS) mice was employed to refine the QTL mapping of Lore1, Lore2, Lore4 and Lore5. ( see Table 1 of text)
  Using 39 progeny from ISCS (Interval-specific congenic strains) lines 11, 4and 13 the mapping of Lore1 was refined to a region of mouse Chromosome 1 bounded by D1Mit180 and D1Mit192.
  Using 79 progeny from ISCS (Interval-specific congenic strains) lines 10, 14, 2 and 5 the mapping of Lore2 was refined to a region of mouse Chromosome 2 bounded by D2Mit403 and D2Mit457.
  Using 24progeny from ISCS (Interval-specific congenic strains) lines 9 and 1 the mapping of Lore4 was refined to a region of mouse Chromosome 11 bounded by D11Mit40 and D11Mit258.
  Using 38 progeny from ISCS (Interval-specific congenic strains) lines 2 and 11 the mapping of Lore5 was refined to a region of mouse Chromosome 15 bounded by D15Mit84 and D15Mit121.
  The evidence for these mappings are shown figuratively in figs 2-5 of the text.